战争应激环境对胃功能及其相关因素影响意义的实验研究

发布时间：2018-08-02 08:47

【摘要】：随着科学技术的发展，，未来战争的环境将会更加残酷。战争环境的应激对于人类产生身心损害也会更加严重。针对这一问题，我们在研究心理性应激对胃功能损害的基础上，通过模仿战争环境条件，观察单一或多种战争环境应激因素对胃的运动功能的损害，其目是为预防战争应激环境对胃功能的损害提供科学的依据。目的：以往人们应用单一应激因素对胃的运动及其相关因素进行了大量的实验和临床研究，并对其相关的机理进行了探讨。但是，对于战争环境对胃的运动的及其相关因素研究相对较少，尤其是对于多种、复合应激因素的影响目前研究报道者鲜见。随着现代科学技术的发展，未来的战争环境和战争状况会更加恶劣和紧迫。由此而造成对人们的应激性影响也会更加严重。所以，研究战争环境对胃肠道功能的损害，具有很重要的使用价值，为未来战争中，应激损伤的防护，提供可靠的理论依据。方法：在建立应激模型的基础上，给予不同试验组以不同的试验干预手段，采用同步对比的观察方法，通过观察单一应激(枪击音应激、睡眠剥夺应激)以及复合环境应激(枪击音—睡眠剥夺应激)对大鼠胃排空、胃电活动、大鼠胃粘膜损害以及与胃运动和胃粘膜相关的某些胃肠道激素
[Abstract]:With the development of science and technology, the environment of future war will be more cruel. The stress of war environment will cause more serious damage to human body and mind. In order to solve this problem, on the basis of studying the damage to gastric function caused by psychological stress, we observed the damage of single or multiple stress factors to gastric motor function by imitating the conditions of war environment. Its aim is to provide scientific basis for preventing the damage of gastric function caused by war stress environment. Objective: in the past, a large number of experiments and clinical studies on gastric motility and related factors were carried out with single stress factor, and the related mechanism was discussed. However, there are few studies on the effects of war environment on gastric motility and its related factors, especially on the effects of multiple stress factors. With the development of modern science and technology, the future war environment and situation will be worse and more urgent. As a result, the stress effect on people will be more serious. Therefore, it is of great value to study the damage to gastrointestinal function caused by war environment, which provides a reliable theoretical basis for the protection of stress injury in future war. Methods: on the basis of establishing stress model, different experimental groups were given different experimental intervention methods. Sleep deprivation stress) and multiple environmental stress (gunshot tone-sleep deprivation stress) on gastric emptying, gastric electrical activity, gastric mucosal damage and certain gastrointestinal hormones associated with gastric motility and gastric mucosa in rats
【学位授予单位】：第四军医大学
【学位级别】：硕士
【学位授予年份】：2005
【分类号】：R82

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