平原人进驻藏北高原地区不同时期的肾脏影响分析

发布时间：2018-10-21 20:36

【摘要】：目的观测藏北高原环境对健康人肾脏的影响。方法随机选择由平原进驻藏北(海拔4507m)当兵6个月、1a、2a的健康军人各80名,均留晨尿测定pH值、比重、尿糖、尿蛋白、尿胆元、尿胆红素、尿潜血、尿酮体、亚硝酸盐和白细胞。取静脉血以苦味酸法测定血尿素氮、血肌酐,根据肌酐值推算内生肌酐清除率(Ccr)。结果进藏6个月的尿潜血、尿蛋白、低尿比重阳性率分别为22.5%、27.5%、23.8%,总阳性率35.0%;进藏1年的阳性率分别为23.8%、28.8%、26.3%,总阳性率38.8%;进藏2年的阳性率分别为25.0%、30.0%、28.8%,总阳性率41.3%。所有被测者尿素氮、肌酐均在正常范围,进藏6个月、1a、2a的Ccr(mL/min)分别为(93.78±4.86)、(92.56±4.69)、(91.96±5.02)。结论藏北高原低氧环境对肾小球、肾小管有不同程度的损害,主要表现尿潜血、尿蛋白、低尿比重的检测异常。
[Abstract]:Objective to observe the effect of environment on kidney of healthy people in northern Tibet Plateau. Methods A total of 80 healthy soldiers were randomly selected from the plain to serve in northern Tibet for 6 months at an altitude of 4507m for 1 a or 2 years. The pH values, specific gravity, urine sugar, urine protein, urinary bile element, urinary bilirubin, urine occult blood, urinary ketone body, nitrite and white blood cell were determined in morning urine. Blood urea nitrogen and creatinine were determined by picric acid method. The creatinine clearance rate (Ccr).) was calculated according to creatinine value. Results the positive rates of urine occult blood, urine protein and low urinary specific gravity in 6 months were 22.5and 27.50.The total positive rate was 35.0cm; the positive rate in one year was 23.82828.826.3cm and the total positive rate was 38.8.The positive rate for 2 years in Tibet was 25.030.030.0328.828.828.8, and the total positive rate was 41.3B. Urea nitrogen and creatinine of all the subjects were in normal range. The Ccr (mL/min) of 1a / 2a was (93.78 卤4.86), () 92.56 卤4.69), (91.96 卤5.02) after 6 months in Tibet. Conclusion hypoxic environment in northern Tibet has different degree of damage to glomerulus and renal tubules, which mainly shows abnormal detection of urine occult blood, urine protein and low urinary specific gravity.
【作者单位】：南京军区福州总医院肾内科西藏那曲军分区医院西藏那曲军分区医院西藏那曲军分区医院西藏那曲军分区医院西藏那曲军分区医院
【分类号】：R82

【相似文献】