累加角度头高斜位下心率、血压、心率变异性与脑血流变化的特征

发布时间：2019-03-02 15:46

【摘要】：目的探讨累加角度头高斜位暴露下 ,正常人体血压、心率、脑血流及心率变异性 (HRV)变化特征 ,为建立飞行员晕厥检查的方法学提供生理依据。方法采用自行研制的多功能双向式医用倾斜床 ,结合先进的十二导联同步心电图描记方法和经颅多普勒脑血流成像技术进行累加角度 ( + 4 5°→ 60°→75°)头高斜位 (HUT)暴露下的心率、血压、HRV和脑血流速率的测量与分析。结果 1 )随着倾斜角度加大 ,暴露时程延长 ,HR逐渐增快 ,SBP逐渐下降 ,DBP逐渐升高 ,PP逐渐缩小 ,与暴露前比较 ,HR、PP和DBP相差非常显著 (P 0 .0 5 ) ;脑血流速率 (包括 :Vs、Vm、Vd)逐渐下降 ,无论与暴露前比 ,或倾斜角度之间比 ,差异十分显著 (P 0 .0 1 ) ;mRR和sdRR逐渐减小。 2 )生理指标与技术指标直线相关分析发现 :在 1min时 ,SBP、DBP、MAP、Vd、sdRR与倾斜角度呈明显正相关 (P 0 .0 1 ) ;在 2 0min时 ,HR和sdRR与倾斜角度呈明显正相关 (P 0 .0 1 ) ,与SBP、PP、Vs、mRR明显负相关 (P 0 .0 1 ) ;暴露时程与HR呈明显正相关 (P 0 .0 1 ) ,与SBP、Vm、Vd、mRR呈明显负相关 (P 0 .0 1 )。 3)生理指标间相关分析发现 :HR与SBP、Vs、Vm、Vd 呈明显负相关 (P 0 .0 1 ) ;SBP与Vd 和mRR呈明显正相关 (P 0 .0 1 ) ;Vs、Vm、Vd 与mRR和sdR
[Abstract]:Aim to investigate the changes of blood pressure, heart rate, cerebral blood flow and heart rate variability (HRV) in normal subjects exposed to cumulative angle head high oblique position, and to provide physiological basis for establishing the methodology of syncope examination in pilots. Methods A multi-functional two-way medical tilting bed was developed by ourselves. Combined with advanced 12-lead synchronous ECG recording method and transcranial Doppler cerebral blood flow imaging technique, heart rate and blood pressure were exposed at a cumulative angle (45 掳/ 60 掳/ 75 掳) at a head high oblique position (HUT). Measurement and analysis of HRV and cerebral blood flow rate. Results 1) with the increase of tilt angle and the prolongation of exposure duration, HR increased, SBP decreased, DBP increased, and PP decreased. Compared with pre-exposure, HR, was observed. The difference between PP and DBP was very significant (P 0.05). The cerebral blood flow rate (including: Vs,Vm,Vd) decreased gradually, regardless of the ratio before exposure or tilt angle, the difference was very significant (P 0.01); mRR and sdRR gradually decreased). 2) the linear correlation analysis between physiological and technical indexes showed that there was a significant positive correlation between SBP,DBP,MAP,Vd,sdRR and tilt angle in 1min (P 0.01); At 2 0min, HR and sdRR were positively correlated with tilt angle (P 0.01), and negatively correlated with SBP,PP,Vs,mRR (P 0.01). The duration of exposure was positively correlated with HR (P 0.01) and negatively correlated with SBP,Vm,Vd,mRR (P 0.01). 3) there was a significant negative correlation between HR and SBP,Vs,Vm,Vd (P 0.01); SBP), Vd and mRR (P 0.01), Vs,Vm,Vd and mRR and sdR (P 0.01).
【作者单位】：航空医学研究所航空医学研究所航空医学研究所航空医学研究所航空医学研究所航空医学研究所
【分类号】：R85

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