针刺治疗免疫性复发性流产的临床研究

发布时间：2018-01-14 10:43

本文关键词：针刺治疗免疫性复发性流产的临床研究　出处：《黑龙江中医药大学》2013年硕士论文　论文类型：学位论文

【摘要】：目的：观察针刺对免疫性复发性流产患者外周血中T淋巴细胞和NK细胞的影响及临床疗效。方法：选取符合纳入标准的60例患者,随机分为治疗组及对照组,每组30例,治疗组予针刺结合主动免疫治疗,对照组予主动免疫治疗。分析治疗前后两组患者外周血中T淋巴细胞(CD4+、CD8+.CD4+/D8+)变化、NK细胞(CD16+CD56+)变化,同时分析临床疗效情况。数据采用SPSS17.0统计软件进行分析。结果：通过治疗,与对照组相比,治疗组患者外周血中CD4+细胞数量及CD4+/CD8+细胞比值显著降低、外周血中的CD8+细胞数量显著增高(P0.05)；外周血NK细胞数量显著降低(P0.05)。治疗组有效率93.33%,对照组有效率73.33%,两组比较具有显著性差异(P0.05)。结论：针刺结合主动免疫治疗疗效确切,更有利于妊娠发展,能良好的体现中西医结合治疗的临床价值；治疗中未见明显不良反应、未见明显毒副作用,治疗成本较低,患者易于接受,适于临床推广。
[Abstract]:Objective: to observe the effect of acupuncture on T lymphocytes and NK cells in peripheral blood of patients with immune recurrent abortion. Methods: 60 patients who met the inclusion criteria were randomly divided into treatment group and control group with 30 cases in each group. The treatment group was treated with acupuncture combined with active immunotherapy. The control group was treated with active immunotherapy. The changes of T lymphocyte CD4 / CD8. CD4 / D8 in peripheral blood before and after treatment were analyzed. The changes of NK cell CD16 CD56 were analyzed by SPSS17.0 software. Results: compared with the control group, the number of CD4 cells and the ratio of CD4 / CD8 cells in the peripheral blood of the patients in the treatment group were significantly lower than those in the control group. The number of CD8 cells in peripheral blood increased significantly (P 0.05). The effective rate of the treatment group was 93.33 and that of the control group was 73.33. The difference between the two groups was significant (P 0.05). Conclusion: acupuncture combined with active immunotherapy is more beneficial to the development of pregnancy and can reflect the clinical value of integrated traditional Chinese and western medicine. There were no obvious adverse reactions, no obvious side effects, low treatment cost, easy acceptance by patients, and suitable for clinical application.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R246.3

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