基于POMDP的不稳定心绞痛中西医结合治疗方案优化研究

发布时间：2018-03-12 22:43

  本文选题：部分可观察马尔科夫决策过程　切入点：不稳定心绞痛　出处：《中国中西医结合杂志》2013年07期 　论文类型：期刊论文

【摘要】：目的初步优化中西医结合防治不稳定心绞痛(unstable angina,UA)的综合治疗方案。方法基于部分可观察的马尔科夫决策过程模型(Partially Observable Markov Decision Process,POMDP)的方法,选择气虚、血瘀、痰浊3个主要证侯要素,对UA住院患者的诊治情况进行深层次数据挖掘、分析,客观评价UA中西医结合的疗效。结果 UA气虚证、血瘀证、痰浊证患者的推荐治疗方案依次为:硝酸酯类+他汀类+氯吡格雷+血管紧张素Ⅱ受体阻滞剂+肝素类+黄芪+党参+茯苓+白术(ADR=0.85077869);硝酸酯类+阿司匹林+氯吡格雷+他汀类+肝素类+当归+红花+桃仁+赤芍(ADR=0.70773000);硝酸酯类+阿司匹林+他汀类+血管紧张素转换酶抑制剂+栝蒌+薤白+半夏+陈皮(ADR=0.72509600)。结论本研究基于POMDP优化了UA的治疗方案,可作为进一步规范和制定中西医结合治疗UA方案的参考。
[Abstract]:Objective to optimize the comprehensive treatment of unstable angina pectoris (UAP) with integrated traditional Chinese and western medicine. Methods based on the partially observable Markov Observable Markov Decision Process-POMDP, three main syndromes, namely deficiency of qi, blood stasis and phlegm turbid, were selected. The diagnosis and treatment of UA inpatients were analyzed and analyzed to evaluate objectively the curative effect of the combination of traditional Chinese and western medicine. Results there were Qi deficiency syndrome, blood stasis syndrome, and blood stasis syndrome. The recommended treatment schemes for patients with phlegm turbid syndrome are as follows: nitrate statin clopidogrel angiotensin 鈪，

本文编号：1603604