隔药灸联合柳氮磺胺吡啶治疗强直性脊柱炎60例临床观察

发布时间：2018-05-01 05:33

本文选题：隔药灸 + 强直性脊柱炎　；参考：《中医杂志》2012年03期

【摘要】：目的观察隔药灸联合柳氮磺胺吡啶(SSZ)治疗强直性脊柱炎(AS)的临床疗效。方法将120例AS患者随机分为观察组和对照组各60例,对照组口服SSZ片,每次0.75g,每日2次,以后每周递增0.25g,至每次1.0g、每日2次维持;观察组在此基础上配合隔药灸(附子、白芥子、吴茱萸)每日1次,治疗3个月后观察疗效,并检测两组患者治疗前后各症状积分、枕墙距、指地距、胸廓活动度,以及血沉(ESR)、C-反应蛋白(CRP)含量。结果观察组和对照组总有效率分别为91.66%、73.33%,两组比较差异有统计学意义(P0.05)。两组患者治疗后各症状积分、指地距、胸廓活动度以及ESR、CRP均较治疗前改善(P0.05或P0.01),两组治疗后比较差异亦有统计学意义(P0.05或P0.01),观察组优于对照组。结论隔药灸配合SSZ在改善患者关节功能及理化指标方面均优于单纯使用SSZ。
[Abstract]:Objective to observe the clinical effect of drug-separated moxibustion combined with sulfamyridine (SSZ) in the treatment of ankylosing spondylitis (ASA). Methods 120 patients with as were randomly divided into two groups: the observation group (n = 60) and the control group (n = 60). The control group received oral SSZ tablets of 0.75 g, twice a day, and then increased by 0.25 g per week to 1.0 g per day for maintenance twice a day. The curative effect was observed after 3 months of treatment. The scores of symptoms, occipital-wall distance, finger and ground distance, chest motion, and the content of ESR C- reactive protein (CRP) were measured before and after treatment in the two groups. Results the total effective rates of observation group and control group were 91.66 and 73.33, respectively. The difference between the two groups was statistically significant (P 0.05). After treatment, the scores of symptoms, finger distance, chest movement and ESR-CRP in the two groups were improved compared with those before treatment (P0.05 or P0.01g). The difference between the two groups after treatment was statistically significant (P0.05 or P0.01A), and the observation group was superior to the control group (P < 0.05). Conclusion Herbal moxibustion combined with SSZ is superior to simple SSZ in improving joint function and physical and chemical indexes.
【作者单位】：青岛市中西医结合医院风湿科;
【基金】：山东省青岛市卫生局资助项目(2010-ZYY001)
【分类号】：R246.1;R593.23

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