针刀结合手法对膝关节骨性关节炎患者关节液中HELIX-Ⅱ、HA含量的影响

发布时间：2018-11-08 21:20

【摘要】：目的:探讨针刀结合手法治疗膝关节骨性关节炎的作用机制。方法:将60例膝关节骨性关节炎患者随机分为观察组与对照组,每组30例。观察组采用针刀结合手法治疗。对照组采用口服双氯芬酸片治疗。观察两组治疗前后关节液中Ⅱ型胶原螺旋肽(HELIX-Ⅱ)、透明质酸(HA)含量的变化。结果:治疗后两组关节液HELIX-Ⅱ含量较治疗前均下降(P0.01,P0.05),但观察组下降明显,与对照组比较,差异有统计学意义(P0.05);HA含量较治疗前均上升(P0.01,P0.05),但观察组上升更显著,与对照组比较,差异有统计学意义(P0.05)。结论:针刀结合手法治疗能使膝关节骨性关节炎患者关节液中HELIX-Ⅱ、HA含量恢复平衡,抑制软骨细胞及基质的继发性损害,从而防治膝关节骨性关节炎。
[Abstract]:Objective: to explore the mechanism of acupuncture combined with manipulation in the treatment of knee osteoarthritis. Methods: 60 cases of knee osteoarthritis were randomly divided into observation group and control group with 30 cases in each group. The observation group was treated with needle knife combined with manipulation. The control group was treated with diclofenac tablets orally. The changes of type 鈪，

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