DCE-MRI在肺内良恶性病变的定量化研究

发布时间：2018-01-31 06:53

本文关键词： 肺磁共振成像动态增强MRI 诊断　出处：《临床放射学杂志》2017年12期 　论文类型：期刊论文

【摘要】：目的利用动态增强MRI(DCE-MRI)的血流动力学参数定量评估肺部病变,并探讨其在鉴别肺内良恶性病变的应用价值。方法搜集本院2014年7月至12月行肺部肿块DCE-MRI扫描的患者42例(恶性病变26例,良性病变16例)。先行肺部常规MRI平扫,然后采用三维快速容积扫描技术(LAVA)先后对病灶进行5次不同翻转角(3°、6°、9°、12°、15°)扫描、再进行DCE-MRI扫描,将5组不同翻转角序列、40期动态增强序列先后导入到Omni-Kinetics分析软件中,计算病灶的K~(tarns)、K_(ep)、V_e等动力学参数。结果恶性病变的K~(tarns)、K_(ep)、Ve值与良性病变有显著性统计学差异(P0.05)。结论 DCE-MRI可以量化分析肺部病变的血流动力学,可以作为定量鉴别肺部病变良、恶性的检查方法。
[Abstract]:Objective to quantitatively evaluate pulmonary lesions with dynamic contrast enhanced MRI (DCE-MRI) hemodynamic parameters. Methods from July 2014 to December, 42 patients (26 malignant lesions) underwent DCE-MRI scanning of pulmonary masses. In 16 cases of benign lesions, conventional MRI scanning was performed first, then the lesions were performed 5 times with 3 掳/ 6 掳/ 9 掳/ 12 掳/ 12 掳reverse angle by 3D rapid volume scanning technique (LAVA). 15 掳) scanning, then DCE-MRI scanning, 5 groups of different inversion angle sequence 40 phase dynamic enhancement sequence into the Omni-Kinetics analysis software successively. The kinetic parameters such as KT tarnsl / Kapp / V _ e of the lesion were calculated. Results the Knsof malignant lesions were found to be Kepp / Kepp). There was significant statistical difference between ve value and benign lesions (P 0.05). Conclusion DCE-MRI can quantitatively analyze the hemodynamics of pulmonary lesions and can be used as a quantitative differential diagnosis of good pulmonary lesions. A malignant examination.
【作者单位】：湖北省鄂东医疗集团黄石市中心医院;湖北理工学院医学院;
【分类号】：R445.2;R734.2
【正文快照】： 肺部病变的良恶性鉴别诊断一直是影像学的重要内容,临床工作中主要是通过观察CT影像形态学及注射对比剂后强化方式进行鉴别。近年来随着磁共振扫描仪快速成像技术的发展,成像时间分辨率及图像质量显著提高,MR影像形态及信号表现、扩散加权成像(diffusion-weighted imaging,DWI

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