乳腺髓样癌的超声造影特征与病理对照

发布时间：2018-02-01 23:34

本文关键词： 乳腺肿瘤癌髓样超声检查造影剂　出处：《中国介入影像与治疗学》2017年03期 　论文类型：期刊论文

【摘要】：目的分析乳腺髓样癌的超声造影特征,并与病理学对照。方法回顾性分析13例乳腺髓样癌患者的超声造影形态学特征,比较造影前后肿块横径、肿块与周围乳腺正常组织的时间-强度曲线定量参数,并进行统计学分析。将超声造影表现与病理表现相对照。结果乳腺髓样癌超声造影显示肿块形态不规则、边界清晰、内部均匀增强分别为10、11、11例,与病理形态学特征相符合。造影前后肿块横径差异无统计学意义(P=0.61),与病理学膨胀性生长方式相符合。与周围乳腺正常组织相比,髓样癌造影剂到达时间和达峰时间显著提前(P=0.034、0.021),峰值强度显著提高(P=0.005),与病理学上病灶内血管密度增高且分布均匀、病灶周边有较大管径血管的特征相符合。结论乳腺髓样癌特征性的超声造影表现有其病理学依据,可作为临床超声诊断和鉴别诊断的依据。
[Abstract]:Objective to analyze the ultrasonographic features of medullary breast carcinoma and compare them with pathology. Methods the morphologic features of 13 cases of medullary carcinoma of breast were analyzed retrospectively and the transverse diameter of the tumor before and after contrast was compared. The quantitative parameters of time-intensity curve between the tumor and the surrounding normal breast tissue were analyzed statistically. The contrast-enhanced ultrasound findings were compared with the pathological findings. Results the shape of the mass was irregular in contrast to the contrast echocardiography. There were 11 cases with clear boundary and 11 cases with homogeneous enhancement, which coincided with the histopathologic features. There was no significant difference in the transverse diameter of the tumor before and after angiography (P 0. 61). Compared with the normal tissues of the surrounding mammary gland, the contrast medium arrival time and peak time of medullary carcinoma were significantly earlier than that of the normal breast tissue. The peak intensity was significantly increased, and the density of blood vessels in the lesion was increased and distributed evenly compared with that in the pathological lesion (P < 0. 005). Conclusion the characteristic contrast-enhanced ultrasonography of medullary carcinoma of breast has its pathological basis and can be used as the basis for clinical diagnosis and differential diagnosis of medullary carcinoma of the breast.
【作者单位】：复旦大学附属华山北院宝山分院超声科;
【分类号】：R737.9;R445.1
【正文快照】： 图1　患者女,52岁,左侧乳腺髓样癌　A.灰阶超声示肿块横径26.1mm;B.造影后示肿块横径26.2mm,且形态不规则,边界清晰,内部呈均匀高增强,周边显示粗大纡曲的动脉血管(箭)　　图2　乳腺髓样癌病理图　A.病灶边界清晰,左侧为病灶,右侧为正常的乳腺组织(HE,×400);B.可见棕色的血管

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