神经内镜和显微镜辅助下切除老年患者垂体腺瘤的临床疗效比较

发布时间：2018-02-05 04:40

本文关键词： 垂体腺瘤神经内镜　出处：《中国老年学杂志》2017年24期 　论文类型：期刊论文

【摘要】：目的评估和比较神经内镜和显微镜下切除老年患者垂体腺瘤的临床疗效。方法老年垂体腺瘤患者100例,随机分为两组(每组50例),分别实施神经内镜和显微镜下经鼻蝶入路垂体腺瘤切除术,分析和比较两组患者手术时间、术中出血量、住院时间、手术全切率、术后并发症和临床预后。结果观察组患者手术时间为(107.9±9.2)min,术中出血量为(59.6±8.6)ml,术后住院天数为(6.0±1.2)d,均明显低于对照组患者[分别为(150.9±16.5)min,(88.6±9.1)ml和(8.1±1.2)d](P0.05)。观察组患者住院期间并发症发生率为6.0%,明显低于对照组患者(18.0%)(P0.05)。观察组的肿瘤全切除率为94%,明显高于对照组(82%)(P0.05)。术后随访6个月,两组患者的临床症状改善率无统计学差异(P0.05)。结论老年患者实施神经内镜下垂体腺瘤切除术具有手术时间短,创伤小,出血量少,手术切除率高,术后并发症少,恢复快等优点。
[Abstract]:Objective to evaluate and compare the clinical effects of endoscopy and microscopical resection of pituitary adenomas in elderly patients. Methods 100 elderly patients with pituitary adenomas were randomly divided into two groups (50 cases in each group). Endoscopic and transsphenoidal transsphenoidal pituitary adenoma resection were performed respectively. The operative time, intraoperative bleeding, hospital stay and total resection rate were analyzed and compared between the two groups. Results the operative time was 107.9 卤9.2 min and the intraoperative bleeding volume was 59.6 卤8.6 ml in the observation group. The postoperative hospitalization time was 6.0 卤1.2 days, which was significantly lower than that in the control group. [It was 150.9 卤16.5 min, respectively. The incidence of complications during hospitalization in the observation group was 6.0%. The total resection rate of tumor in the observation group was 94, which was significantly higher than that in the control group. There was no significant difference in the improvement rate of clinical symptoms between the two groups (P 0.05). Conclusion the elderly patients with neuroendoscopic pituitary adenoma resection have the advantages of short operation time, less trauma, less bleeding, and high resection rate. There are few complications and quick recovery after operation.
【作者单位】：武警江苏省总队医院医务室;武警江苏省总队医院神经外科;上海市第一人民医院神经外科;
【分类号】：R736.4
【正文快照】： 1武警江苏省总队医院神经外科2上海市第一人民医院神经外科垂体腺瘤是神经外科一种常见的良性肿瘤,以视力视野障碍和内分泌紊乱为主要临床表现。手术切除是目前治疗垂体腺瘤的主要手段,并以经鼻蝶入路的微创手术为主[1]。显微镜辅助下经鼻蝶入路的垂体腺瘤切除术是目前临床上

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