甲状腺乳头状癌淋巴结转移规律及影响因素分析

发布时间：2018-04-04 15:40

本文选题：甲状腺肿瘤　切入点：乳头状癌　出处：《中山大学学报(医学科学版)》2017年01期

【摘要】：【目的】探讨甲状腺乳头状癌的淋巴结转移规律,分析其影响因素。【方法】回顾性分析我院自2011年1月至2015年12月手术治疗甲状腺乳头状癌病人375例的临床资料,对其原发灶特点、淋巴结转移规律进行了总结。【结果】本组患者均为甲状腺乳头状癌,颈部淋巴结总转移率为67.47%,中央组淋巴结转移率为64.27%,颈侧组淋巴结转移率为36.53%。原发灶肿瘤直径大于1 cm、肿瘤突破包膜、侵犯肌肉时颈淋巴结转移发生率明显升高(P0.05)。【结论】甲状腺乳头状癌最常见的淋巴结转移为中央组淋巴结,初次手术应常规清扫双侧中央组淋巴结,当肿块直径大于1 cm或癌肿突破甲状腺包膜和/或侵犯肌肉时宜同时清扫同侧的颈侧组淋巴结。
[Abstract]:[objective] to investigate the lymph node metastasis of papillary thyroid carcinoma and analyze its influencing factors. [methods] the clinical data of 375 patients with papillary thyroid carcinoma treated by surgical treatment from January 2011 to December 2015 were analyzed retrospectively.[results] all patients were papillary thyroid carcinoma, the total metastasis rate of cervical lymph node was 67.47, the lymph node metastasis rate of central group was 64.27 and the lymph node metastasis rate of cervical side group was 36.53.The diameter of primary tumor is more than 1 cm. The incidence of cervical lymph node metastasis is significantly increased when the tumor breaks through the capsule and invades the muscle. [conclusion] the most common lymph node metastasis of papillary thyroid carcinoma is central lymph node.The primary operation should be routine dissection of bilateral central lymph nodes. When the diameter of the tumor is larger than 1 cm or the tumor breaks through the thyroid capsule and / or invades the muscle, the ipsilateral cervical lymph nodes should be dissected at the same time.
【作者单位】：中山大学附属第三医院岭南医院普通外科;中山大学附属第三医院甲状腺乳腺外科;
【基金】：广东省自然科学基金(2014A030313193)
【分类号】：R736.1

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