外泌体及其在肿瘤诊疗中的作用

发布时间：2018-05-09 11:30

本文选题：外泌体 + 微小RNA　；参考：《上海交通大学学报(医学版)》2017年07期

【摘要】：外泌体是多种活细胞分泌的有被小泡,包含有蛋白质、脂质、核酸及多种其他生物大分子。外泌体在很多病理生理过程中发挥重要作用,如免疫中抗原呈递、组织损伤修复、肿瘤的生长与迁移等。肿瘤来源或肿瘤相关的外泌体在调控肿瘤发生和发展的过程中扮演重要角色,对肿瘤外泌体的分析和检测可以辅助肿瘤的早期诊断为患者提供新的治疗方法。该文从外泌体的起源、组成及其在肿瘤发生、发展、迁移、诊断治疗等方面进行综述,为肿瘤治疗提供新的思路。
[Abstract]:Exocrine is a vesicle secreted by a variety of living cells, including proteins, lipids, nucleic acids, and a variety of other biological macromolecules. Exocrine plays an important role in many pathophysiological processes, such as antigen presentation, tissue damage repair, tumor growth and migration, and tumor origin or tumor related exocrine in regulating tumor hair. In the process of birth and development, the analysis and detection of the tumor exocrine can assist the early diagnosis of the tumor to provide a new treatment for the patients. This article reviews the origin of the exocrine, its composition and its development, migration, diagnosis and treatment, and provides a new way of thinking for the treatment of tumor.

【作者单位】：上海交通大学医学院附属仁济医院消化内科;上海交通大学医学院附属瑞金医院检验系;
【基金】：上海市自然科学基金面上项目(14ZR1425100)~~
【分类号】：R73-3

【相似文献】