弥散张量成像的部分各项异性值和表观弥散系数值在胶质瘤分级中应用的Meta分析
发布时间：2018-06-17 03:00
本文选题：弥散张量成像 + 胶质瘤 ； 参考：《吉林大学学报(医学版)》2017年02期
【摘要】：目的:采用Meta分析方法阐明弥散张量成像(DTI)的部分各项异性(FA值)值和表观弥散系数(ADC)值在胶质瘤分级中应用的意义,为胶质瘤治疗方案的选择与预后判断提供参考。方法:计算机检索PubMed数据库、EMBASE数据库、中国知网(CNKI)、万方数据库和维普数据库,手工检索神经外科学杂志、神经影像学杂志和有关神经外科的学术会议论文集,回溯检索综述性论文的参考文献,按纳入与排除标准选择病例系列研究、评价研究质量,采用Review Manager 5.2软件对所提取数据进行Meta分析。结果:共有9篇文献入选。低级别胶质瘤(LGG)肿瘤实质区的FA值低于高级别胶质瘤(HGG)肿瘤实质区的FA值,差异有统计学意义(χ~2=11.94,df=8,P=0.15;I~2=33%,Z=2.78,P=0.005;WMDFA值=-0.02,95%CI:-0.03~-0.01);LGG肿瘤实质区的ADC值高于HGG肿瘤实质区的ADC值,差异有统计学意义(χ~2=5.26,df=4,P=0.26;I~2=24%,Z=2.19,P=0.03;WMD_(ADC值)=0.15,95%CI:0.02~0.28)。结论:胶质瘤实质区FA值越大,ADC值越低,胶质瘤的级别越高;DTI的FA值和ADC值有助于确定胶质瘤的分级。
[Abstract]:Objective: to elucidate the value of partial heterosexual FA value and apparent diffusion coefficient of diffusion Zhang Liang imaging (DTI) in glioma grading by meta-analysis, so as to provide a reference for the treatment of glioma and the judgement of prognosis. Methods: PubMed database was searched by computer, CNKIX, Wanfang database and Weip database were searched by computer, neurosurgery journal, neuroimaging journal and proceedings of neurosurgery were searched by hand. Retrospective retrieval of the literature of summary papers, selection of case series studies according to inclusion and exclusion criteria, evaluation of research quality, Meta-analysis of extracted data using Review Manager 5.2 software. Results: a total of 9 articles were selected. 浣庣骇鍒兌璐ㄧ槫(LGG)鑲跨槫瀹炶川鍖虹殑FA鍊间綆浜庨珮绾у埆鑳惰川鐦，
本文编号：2029347
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