迭代重组iDose~4技术和IMR技术在胃肠道肿瘤术后低剂量随访中的应用研究

发布时间：2019-01-26 10:19

【摘要】：目的探讨迭代重组iDose4技术和基于模型的全迭代重组(IMR)技术在胃肠道肿瘤术后低剂量随访中的应用价值,并比较迭代重组i Dose4和IMR对图像质量的影响。方法将30例胃肠道肿瘤术后患者纳入此项研究。在初诊和6个月后复诊时分别进行腹部CT平扫和增强(常规剂量和低剂量)扫描,采用滤波反投影(FBP)技术重组常规剂量扫描图像门静脉期原始数据,采用迭代重组iDose4技术和IMR技术重组低剂量扫描图像门静脉期原始数据,得到3组图像,包括A组(常规剂量组)、B1组(低剂量i Dose4组)、B2组(低剂量IMR组),将门静脉期扫描数据作为研究对象,对图像进行客观和主观分析,客观分析包括测量肝脏的CT值,噪声及信噪比(SNR),主观分析包括对图像进行质量评分,并比较辐射剂量。结果低剂量扫描较常规剂量扫描辐射剂量平均降低了51.47%(P0.05)。图像主观评分差异无统计学意义(P0.01),三组图像均能满足诊断要求。图像客观评价中,三组图像CT值相仿(P0.05),差异无统计学意义。三组图像的噪声、SNR值和对比噪声比(CNR)值之间的差异有统计学意义(P0.05),B1组较A组之间图像噪声和SNR值之间的差异均无统计学意义(P0.05),B2组较A组图像噪声明显降低、SNR值明显提高,差异均有统计学意义(P0.01),B1组与B2组较A组CNR值均提高,差异均有统计学意义(P0.01),B2组提高更显著,且B1与B2组之间差异有统计学意义(P0.01)。结论采用迭代重组i Dose4技术和IMR技术,对胃肠道肿瘤患者术后进行低剂量CT随访,在大幅降低辐射剂量的同时均能保证图像质量可满足诊断要求,并且迭代重组IMR技术较iDose4技术的图像噪声低、图像质量高。
[Abstract]:Objective to investigate the application value of iterative recombinant iDose4 technique and model-based total iterative recombinant (IMR) technique in low-dose follow-up of gastrointestinal neoplasms, and to compare the effects of iterative recombination I Dose4 and IMR on image quality. Methods 30 patients with gastrointestinal neoplasms after operation were included in the study. Abdominal CT plain scan and enhancement (conventional dose and low dose) scan were performed at first visit and 6 months later. The original data of portal vein phase were reconstructed by filtered backprojection (FBP) technique. The original data of portal vein phase of low-dose scanning images were reconstructed by iterative recombination iDose4 technique and IMR technique. Three groups of images were obtained, including group A (routine dose group), group B1 (low dose I Dose4 group), group B2 (low dose IMR group), group B (low dose IMR group). The scanning data of portal vein were used as the object of study. The objective analysis included the measurement of CT value of liver, the subjective analysis of noise and signal-to-noise ratio (SNR), including the evaluation of image quality, and the comparison of radiation dose. Results the average radiation dose of low dose scan was 51.47% lower than that of conventional dose scan (P0.05). There was no significant difference in image subjective score (P0.01). All three groups of images could meet the diagnostic requirements. In the objective evaluation of images, the CT values of the three groups were similar (P0.05), the difference was not statistically significant. The difference of noise, SNR value and contrast noise ratio between three groups was statistically significant (P0.05), but there was no significant difference between group B1 and group A in image noise and SNR value (P0.05). The image noise and SNR value of group B2 were significantly lower than those of group A (P0.01). The CNR values of group B1 and group B2 were significantly higher than those of group A (P0.01), and the increase of CNR in group B2 was more significant than that in group A (P0.01). There was significant difference between group B1 and group B2 (P0.01). Conclusion by using iterative recombination I Dose4 and IMR techniques to follow up the patients with gastrointestinal cancer with low dose CT, the image quality can be guaranteed to meet the diagnostic requirements while the radiation dose is significantly reduced. And the iterative recombination IMR technique has lower image noise and higher image quality than iDose4 technology.
【作者单位】：南京医科大学鼓楼临床医学院;南京大学医学院附属鼓楼医院;
【基金】：南京市医学科技发展一般性课题资助项目(编号:YKK13078) 江苏省卫生厅青年科研课题资助项目(编号:Q201411)
【分类号】：R445.2;R735

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