化痰通脉汤治疗冠心病不稳定型心绞痛（痰瘀互阻型）的临床疗效观察

发布时间：2018-02-21 03:51

本文关键词： 化痰通脉汤不稳定型心绞痛痰瘀互阻同型半胱氨酸　出处：《黑龙江中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:通过观察化痰通脉汤治疗冠心病不稳定型心绞痛(痰瘀互阻型)的临床疗效,评价其安全性和有效性。方法:将符合入选条件的60例不稳定型心绞痛(痰瘀互阻型)患者随机分为对照组和治疗组各30例,对照组给予西医基础治疗,治疗组给予西医基础治疗联合化痰通脉汤,分别于治疗前及治疗2周后记录出两组患者中医证侯积分,同型半胱氨酸水平,心电图变化,观察其临床疗效。结果:1.中医证候疗效:两组治疗后中医证候疗效均较治疗前改善,治疗组明显优于对照组,两组具有显著差异性(P0.05);2.心电图疗效:两组治疗后均有改善,治疗组总有效率63.33%,对照组总有效率56.67%,两组比较无统计学意义(P0.05);3.同型半胱氨酸值的比较:两组治疗后数值较疗前均有下降(P0.01),治疗后治疗组明显低于对照组,两组具有明显差异性(P0.05);结论:1.化痰通脉汤能够降低冠心病不稳定型心绞痛(痰瘀互阻型)患者的中医证候积分,改善患者临床症状;2.化痰通脉汤能够减轻不稳定心绞痛(痰瘀互阻型)患者的心绞痛症状,改善心电图缺血状态。3.化痰通脉汤能够降低不稳定心绞痛(痰瘀互阻型)患者血同型半胱氨酸含量、抑制炎症反应、稳定斑块。
[Abstract]:Objective: to observe the clinical effect of Huatan Tongmai decoction on unstable angina pectoris of coronary heart disease. Methods: 60 patients with unstable angina pectoris (phlegm and blood stasis mutual obstruction) were randomly divided into two groups: control group (n = 30) and treatment group (n = 30). The treatment group was treated with western medicine combined with Huatan Tongmai decoction. The TCM syndromes score, homocysteine level and electrocardiogram of the two groups were recorded before and 2 weeks after treatment. Observe its clinical curative effect. Results 1. TCM syndromes curative effect: after treatment, the curative effect of TCM syndrome in the two groups was improved compared with that before treatment, the treatment group was obviously superior to the control group, and the two groups had significant difference (P 0.05). 2. Electrocardiogram effect: there was improvement in both groups after treatment. The total effective rate of the treatment group was 63.33 and the total effective rate of the control group was 56.67. There was no significant difference between the two groups. Conclusion (1) Huatan Tongmai decoction can reduce TCM syndromes integral of patients with unstable angina pectoris (phlegm and blood stasis obstruction type) of coronary heart disease. To improve the clinical symptoms of patients 2.Huatan Tongmai decoction can alleviate the symptoms of angina pectoris in patients with unstable angina pectoris (phlegm and blood stasis obstruction type). Improve the ischemic state of ECG .3.Huatan Tongmai decoction can reduce the content of homocysteine in blood of patients with unstable angina pectoris (phlegm and blood stasis mutual obstruction), inhibit inflammatory reaction and stabilize plaque.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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