理郁升陷汤加减治疗胃下垂（肝胃不和型）的临床研究

发布时间：2018-03-06 20:42

本文选题：胃下垂　切入点：理郁升陷汤　出处：《河南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本研究通过观察理郁升陷汤加减治疗胃下垂(肝胃不和型)在中医证候学、X线钡餐、总有效率等方面来评价其临床疗效及安全性,试从理论和临床研究两个方面探索其作用机理,从而为中医药治疗本病提供理论依据。方法:将74例门诊患者按就诊顺序,采用完全随机数字表法,按1:1比例将所观察病例随机分为治疗组37例(脱落2例),对照组37例(脱落2例),治疗组给予理郁升陷汤加减治疗,每日早晚分服,每次1袋(100ml,中药饮片的购置与药液的煎煮由河南省中医院中药房专人负责)。对照组给予口服胃苏冲剂治疗,每日3次,每次1袋。治疗12周后,观察两组治疗前后患者的中医证候疗效、X线钡餐值以及安全性指标和不良反应事件。结果:(1)中医证候疗效方面:按照中医证候疗效评定标准进行评价分析,治疗组总有效率为94.27%;对照组总有效率为74.28%。两组相比有统计学差异(P0.05);(2)X线钡餐值监测方面:治疗组总有效率为80.00%;对照组为51.40%。两组相比有统计学差异(P0.05);(3)综合疗效比较:治疗组痊愈1例、好转6例、有效26例、无效2例,总有效率为94.30%;对照组痊愈0例、好转6例、有效18例、无效11例,总有效率为68.60%.两组相比有统计学差异(P=0.040.05)。结论:理郁升陷汤加减治疗胃下垂(肝胃不和型)疗效确切,能显著、全面改善胃下垂患者的中医证候、X线钡餐,总有效率高,临床应用安全有效,是治疗胃下垂的有效方剂。
[Abstract]:Objective: to evaluate the clinical efficacy and safety of Liyusheng decoction in the treatment of gastric ptosis (hepatogastric disharmony type) in the aspects of TCM syndromes, X-ray barium meal, total effective rate and so on. In order to provide a theoretical basis for the treatment of this disease, 74 outpatients were treated in full random digital table, according to the order of seeing a doctor, so as to provide a theoretical basis for the treatment of the disease. According to the ratio of 1: 1, the observed cases were randomly divided into treatment group (n = 37) and control group (n = 37). Each bag was 100 ml, the purchase of traditional Chinese medicine tablets and the decoction of medicine solution were handled by the Chinese medicine department of Henan traditional Chinese Medicine Hospital. The control group was treated with oral Weisu granule, 3 times a day, 1 bag each time. After 12 weeks of treatment, the control group was treated with Weisu granules. Observe the curative effect of TCM syndrome barium meal, safety index and adverse events before and after treatment in two groups. Results the curative effect of TCM syndromes was evaluated according to the evaluation standard of TCM syndromes. The total effective rate of the treatment group was 94.27; the total effective rate of the control group was 74.28. There was statistical difference between the two groups: the total effective rate of the treatment group was 80.005; the control group was 51.40. There was statistical difference between the two groups. In the treatment group, 1 case was cured, 6 cases were improved, 26 cases were effective, 2 cases were ineffective, the total effective rate was 94.30%, while in the control group, 0 cases were cured, 6 cases were improved, 18 cases were effective, 11 cases were ineffective. The total effective rate was 68.60. There was statistical difference between the two groups (P 0.040.05). Conclusion: Liyusheng decoction is effective in treating gastric ptosis (hepatogastric disharmony type), and it can improve the TCM syndromes of patients with gastric prolapse, and the total effective rate is high. Clinical application is safe and effective, is an effective prescription for the treatment of gastric prolapse.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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