多囊卵巢综合征易感体质的调查分析

发布时间：2018-03-17 17:23

  本文选题：PCOS　切入点：易感体质　出处：《河南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本研究旨在通过体质调查量表对郑州地区多囊卵巢综合征(Polycystic Ovarian Syndrome,PCOS)患者进行体质统计,了解PCOS患者体质类型构成状况,计算出PCOS患者的易感体质,并分析出易感体质与促黄体生成素(Luteinizing hormone,LH)、睾酮(Testostrn,T)、胰岛素抵抗(Insulin Resistance,IR)的相关性,从而尽早对易感体质进行药物、饮食、运动等调体治疗,针对性预防对于症状典型但激素水平测定正常的患者进一步出现IR、高雄激素血(Hyperandrogenism,HA)、高LH等生化病理表现,为PCOS的早期预防提供新思路和依据。方法:选取2015年4月~2016年2月就诊于河南中医药大学第一附属医院妇科门诊的113例确诊为PCOS的郑州地区患者,作为本研究的调查对象。先由受过培训的专业人员对表格进行讲解,再由患者在安静环境下独立填写表格,最后由工作人员将所收集的调查结果进行转化分计算并录入Excel,建立SPSS数据库。计数资料采用独立四表格Pearson(T≥5,n≥40)?2检验进行分析,计量资料首先采用单样本k-s检验法对其进行正态性和方差齐性检验,如为正态分布且方差齐,则进行两个独立样本的t检验法进行分析,若不符合正态分布,则进行两独立样本的非参数检验法进行分析。结果:(1)郑州地区113例PCOS患者体质分布情况:阳虚质52例(46.02%)、血瘀质22例(19.47%)、痰湿质13例(11.5%)、气郁质11例(9.73%)、湿热质5例(4.42%)、阴虚质3例(2.65%)、气虚质3例(2.65%)平和质2例(1.77%)、特禀质2例(1.77%);其中非阳虚质共61例(53.98%);(2)阳虚质组患者的平均年龄为26.1±3.3岁,非阳虚质组平均年龄为26.3±3.7岁,两组比较(P0.05)无显著性差异,无统计学意义;(3)两组患者初潮年龄比较,阳虚质组平均初潮年龄比非阳虚质组患者的平均初潮年龄晚1年,有统计学意义(P0.05);(4)两组患者LH异常升高(LH/FSH2)的发生率,阳虚质组明显高于非阳虚质组,有统计学意义(P0.05);(5)阳虚质组与非阳虚质组HA发生率比较,阳虚质组HA的发生率高于非阳虚质组,差异有统计学意义(P0.05);(6)两组患者肥胖发生情况:阳虚体质组肥胖者28(53.84%)人,非阳虚体质组肥胖者13(21.31%)人,两组比较,差异有统计学意义(P0.05)。结论:(1)阳虚体质是PCOS的易感体质;(2)阳虚体质患者平均初潮年龄比非阳虚体质患者的平均初潮年龄推迟将近1年。提示青春期的体质状态会影响患者月经初潮年龄,阳虚体质女性的初潮年龄一般会推迟,因此应早于青春期就要重视对体质的调理,预防PCOS的发生;(3)阳虚体质的PCOS患者发生LH异常升高、IR、HA及肥胖的几率均较非阳虚体质患者大,应重视对PCOS阳虚体质进行调体治疗,预防相关疾病的发生。
[Abstract]:Objective: the purpose of this study was to investigate the constitution of polycystic Ovarian syndromes (PCOSs) patients with polycystic ovary syndrome (PCOS) in Zhengzhou area, and to find out the constitution of PCOS patients' physique types, and to calculate the susceptible constitution of PCOS patients. We also analyzed the correlation between susceptible constitution and luteinizing hormone (LHH), testosterone (Testostrn), insulin resistance (IRR), so as to treat susceptible constitution with medicine, diet, exercise and so on as soon as possible. For the patients with typical symptoms but normal hormone levels, there were further biochemical pathological manifestations such as IRI, hyperandrogenismHAI, high LH and so on. Methods: from April 2015 to February 2016, 113 patients diagnosed as PCOS in the gynecological outpatient department of the first affiliated Hospital of Henan University of traditional Chinese Medicine were selected. As the subject of this study, the form was explained by trained professionals, and then the patient filled out the form independently in a quiet environment. Finally, the investigation results collected by the staff were transformed into Excel, and the SPSS database was established. The counting data were counted by independent four tables, Pearson(T 鈮，

本文编号：1625721