基于运气理论应用陈氏运气证治方紫菀汤治疗肺虚感寒兼郁热型外感咳嗽的临床研究

发布时间：2018-03-21 04:13

本文选题：运气证治方紫菀汤　切入点：外感咳嗽　出处：《南京中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨五运六气理论临床运用前景,选择陈无择《三因极—病证方论》中记载的运气证治方紫菀汤,观察该运气证治方治疗肺虚感寒兼郁热型外感咳嗽的临床疗效,以揭示在五运六气理论指导下,运用运气证治方(紫菀汤)的价值优势,充分显示中医"天人相应"理论在外感咳嗽辨治中的价值,以丰富外感咳嗽中医辨治手段,并扩大紫菀汤的应用范围。方法:此研究以肺虚感寒,兼郁热证型的外感咳嗽患者为研究对象,采用小样本对照试验,随机分组,中药治疗组和西药对照组比例为2:1,中药组60例,西药组30例。中药组予紫菀汤治疗,疗程:4周,随访半年;西药组予惠菲宁治疗。疗程:4周,随访半年。对比两组治疗前后各观察点的中医证候总积分(肺虚感寒,兼郁热证)、肺虚症状积分以及LCQ评分,并观察其起效时间和复发次数。结果:(1)总体疗效:中药组总有效率90%;西药组总有效率73.3%;根据SPSS2.0统计软件分析,中药组的总体疗效大于西药组(P=0.0430.05)。(2)中医证候总积分(肺虚感寒,兼郁热证):根据参与试验的患者试验数据,两组药物治疗前后的症状积分均逐步降低,但中药组相较于西药组更加有效的降低症状积分,缓解临床症状(P0.05)。(3)肺虚症状积分:参与试验的患者的肺虚症状经中药与西药治疗后,症状积分均逐步降低,治疗前后对照,中药组治疗肺虚症状具有明显的效果(P0.05)。(4)LCQ评分:参与试验的外感咳嗽患者,经治疗后,各区域总分逐步上升,两组治疗前后相比,中药组具有更好的控制咳嗽的效果(P0.05)。(5)起效时间及复发次数:两组药物服用后,相较于西药组,中药组起效时间更快(P0.01)。根据治疗后半年内的随访数据,中药组能更加有效增强体质,减少咳嗽复发次数(P0.05)。
[Abstract]:Objective: to explore the prospect of clinical application of the theory of "five Transport and six Qi", select Chen Wu-xuan "San Jinji-Disease Syndrome Formula", and observe the clinical curative effect of this kind of lucky syndrome prescription on the treatment of lung deficiency, cold and stagnation heat type exogenous cough. Under the guidance of the theory of "five Transport and six Qi" and using the value advantage of "Qi Zhi Fang" (Aster decoction), this paper fully shows the value of the theory of "Heaven and Man corresponding" in the treatment of exogenous cough, and enriches the means of TCM differentiation and treatment of exogenous cough. Methods: in this study, external cough patients with deficiency of lung and heat syndrome were selected as the research objects, and small sample control trial was used to group them randomly. The proportion of traditional Chinese medicine treatment group and western medicine control group was 2: 1, 60 cases in traditional Chinese medicine group and 30 cases in western medicine group. The traditional Chinese medicine group was treated with Aster decoction for 4 weeks and followed up for half a year; the western medicine group was treated with Huifining for 4 weeks. Follow up for half a year. Compare the total score of TCM syndromes before and after treatment between the two groups (lung deficiency feeling cold, stagnation and heat syndrome, lung deficiency symptom score and LCQ score). Results: the total effective rate of traditional Chinese medicine group was 90 and that of western medicine group was 73.3 percent. According to SPSS2.0 statistical software analysis, the total curative effect of traditional Chinese medicine group was greater than that of western medicine group. According to the experimental data of the patients participating in the experiment, the symptom scores of the two groups decreased gradually before and after treatment, but the Chinese medicine group was more effective than the western medicine group in reducing the symptom score. Symptom score of lung deficiency: after treatment with traditional Chinese medicine and western medicine, the symptom score of patients with lung deficiency decreased gradually, compared with that before and after treatment. After treatment, the total scores of the patients with external cough in the test group increased gradually, compared with the two groups before and after treatment, the Chinese medicine group had obvious effect in treating the symptoms of lung deficiency and the score of LCQ was higher than that of the control group before and after treatment, and the scores of the two groups were higher than those of the control group. The Chinese medicine group had better effect of controlling cough (P0.05. 5) the time of onset and the times of recurrence: after the two groups of drugs were taken, the onset time of the Chinese medicine group was faster than that of the western medicine group. According to the follow-up data of half a year after treatment, the Chinese medicine group had a faster onset time than the western medicine group. The traditional Chinese medicine group can strengthen the physique more effectively, reduce the cough relapse times P0.05.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R256.11

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