运用行气化痰、消瘀通络法治疗老年单纯收缩期高血压（痰瘀互阻型）的临床研究

发布时间：2018-04-11 04:21

本文选题：老年单纯收缩期高血压 + 泽蒺降压颗粒　；参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:通过运用行气化痰、消瘀通络法治疗老年单纯收缩期高血压(痰瘀互阻型)的临床研究,证明本治法可有效调控老年单纯收缩期高血压患者的血压,改善其临床症状,并能证明其安全可靠。方法:本研究通过随机对照法将72例患者分为两组进行临床研究。治疗过程中,治疗组通过口服泽蒺降压颗粒控制血压;对照组则口服清眩降压片。疗程为28天。观察治疗前后两组中医证候及血压情况的变化,并运用统计学方法进行疗效判定及评估相关安全性。结果:72例患者均完成试验,无不良反应。治疗组在降低血压及改善证候方面的总有效率为88.88%、91.66%;对照组则为72.22%、75.00%。经秩和检验,降压疗效:z=-2.042,P=0.041;中医证候总疗效:z=-1.991,P=0.047;治疗后证候总积分两组组间比较:z=-3.377,P=0.012。结论:据试验数据统计分析,在有效控制血压方面,有统计学意义(P0.05)。在改善症状方面,尤其在改善头晕、头痛、失眠、胸闷的中医症状方面,经秩和检验,治疗组疗效优于对照组。入组的患者均完成试验,无不良反应,证明临床安全可靠。
[Abstract]:Objective: to prove that this method can effectively regulate the blood pressure and improve the clinical symptoms of aged patients with simple systolic hypertension (phlegm and blood stasis mutual obstruction type) by using the methods of removing qi and removing phlegm and removing blood stasis and dredging collaterals.It can prove its safety and reliability.Methods: 72 patients were randomly divided into two groups.In the course of treatment, the treatment group controlled blood pressure by taking Zaijiangya granule, while the control group took Qingxuan Jiangya tablet.The course of treatment was 28 days.The changes of TCM syndromes and blood pressure were observed before and after treatment.Results all 72 patients completed the test without adverse reaction.The total effective rate of lowering blood pressure and improving syndromes in the treatment group was 88.88 and 91.66, while that in the control group was 72.22 and 75.00.The results of rank sum test showed that the effect of hypotension was: 1: ZX -2.042% P0. 041; the total curative effect of TCM syndromes was 1: ZG-1. 991U PU-0.047; after treatment, the total score of syndromes of the two groups was compared with that of the two groups.Conclusion: according to the statistical analysis of experimental data, there is statistical significance in the effective control of blood pressure (P 0.05).In improving symptoms, especially in improving the symptoms of dizziness, headache, insomnia, chest tightness, the curative effect of the treatment group was better than that of the control group by rank sum test.All patients in the group completed the test, no adverse reactions, clinical safety and reliability.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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