全蝎软膏治疗下肢静脉性溃疡（湿热下注型）的临床观察

发布时间：2018-05-03 05:20

本文选题：全蝎软膏 + 下肢静脉性溃疡　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:观察全蝎软膏局部外用对下肢静脉性溃疡(湿热下注型)患者的疮面面积、溃疡面渗液量、疮面菌群检出率及中医症候积分的影响,以证实全蝎软膏局部外用对治疗下肢静脉性溃疡(湿热下注型)的临床效果。方法:将符合纳入标准的下肢静脉性溃疡(湿热下注型)的门诊病人87例,按随机数字表法分为治疗组(43例)和对照组(44例),实际治疗组脱落3例,对照组脱落4例,两组各40例。治疗组给予基础治疗及疮面外涂全蝎软膏;对照组给予基础治疗及疮面外用红霉素软膏,治疗一个月(一个疗程),观察两组病人治疗前、两周后、一月后的疮面面积、溃疡面渗液量、中医证候积分改变情况,以及治疗前后疮面菌群检出率,并对试验数据进行统计分析。结果:1.一个疗程后,两组病人中医症候积分比较,差异具有统计学意义(P0.05);2.一个疗程后,两组病人溃疡面积及溃疡面渗液量分别比较,差异有统计学意义(p0.05);3.一个疗程后,两组病人疮面菌群检出率比较,治疗组疮面菌群检出率6例,对照组溃疡面菌群检出率15例,差异无统计学意义(p0.05)。4.一个疗程后,两组病人临床疗效比较,治疗组临床总有疗效率97.50%,对照组临床总疗效率87.50%,差异有统计学意义(p0.05)。结论:1.全蝎软膏外用能明显改善下肢静脉性溃疡(湿热下注型)病人的症状。2.全蝎软膏外用治疗下肢静脉性溃疡(湿热下注型),具有缩小溃疡面积、减少疮面渗液量、提高疮面愈合率的作用。3.全蝎软膏外用能够明显抑制下肢静脉性溃疡(湿热下注型)疮面细菌生长。
[Abstract]:Objective: to observe the effect of Scorpion ointment on the area of ulcer surface, the quantity of exudation, the detection rate of bacterial flora and the integral of TCM symptoms in patients with venous ulcer of lower extremity (damp-heat betting type). To confirm the clinical effect of Scorpion ointment in treating venous ulcer of lower extremity. Methods: 87 outpatients with venous ulcer of lower extremity (damp-heat betting type) were randomly divided into treatment group (n = 43) and control group (n = 44). The actual treatment group (n = 3) and the control group (n = 4) were divided into two groups: the control group (n = 4), the control group (n = 4) and the control group (n = 4). There were 40 cases in each group. The patients in the treatment group were treated with basic treatment and scorpion ointment, and the control group were treated with Erythromycin ointment for one month (a course of treatment). The quantity of ulcer surface effusion, the change of TCM syndrome integral, and the detection rate of bacterial flora before and after treatment were analyzed statistically. The result is 1: 1. After a course of treatment, the two groups of patients compared the TCM symptom score, the difference was statistically significant (P 0.05). After a course of treatment, the area of ulcer and the amount of exudation on the ulcer surface of the two groups were compared, and the difference was statistically significant (P 0.05). After one course of treatment, the detection rate of the bacterial flora on the sore surface was compared between the two groups. There were 6 cases in the treatment group and 15 cases in the control group. The difference was not statistically significant (P 0.05). After one course of treatment, the clinical curative effect of the two groups was compared. The total curative effect rate of the treatment group was 97.50, and that of the control group was 87.50. The difference was statistically significant (P 0.05). Conclusion 1. Scorpio ointment can significantly improve the symptoms of lower extremity venous ulcers (damp-heat betting type) patients. 2. Scorpio ointment was used to treat venous ulcer of lower extremity. It can reduce the area of ulcer, reduce the amount of exudation and increase the healing rate of sore surface. Scorpion ointment can significantly inhibit the growth of bacteria on the sore surface of venous ulcer of lower extremity.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R269

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