舒心汤治疗老年抑郁的临床研究

发布时间：2018-05-03 06:13

本文选题：老年抑郁 + 中医　；参考：《内蒙古中医药》2017年02期

【摘要】：目的:探究舒心汤治疗老年抑郁的临床疗效。方法:根据CCMD-3及中医郁证诊断标准入组97例老年抑郁病例,随机分为中药组与西药组,其中脱落4例(中药组1例,西药组3例),剔除后中药组53例,西药组40例。中药组用舒心汤治疗,西药组用盐酸舍曲林片治疗。记录两组的治疗效果。结果:治疗前两组汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)评分及中医症状评分比较差异无统计学意义(P0.05),治疗8周后中药组HAMD、SDS量表评分及中医症状评分优于西药组,差异具有统计学意义(P0.05)。治疗8周后中药组总有效率94.3%高于西药组75.0%,差异具有统计学意义(P0.05)。中药组不良反应发生率9.4%低于西药组30.0%,差异具有统计学意义(P0.05)。结论:舒心汤治疗老年抑郁效果优于盐酸舍曲林片,且安全性高。
[Abstract]:Objective: To explore the clinical effect of Shuxin Decoction in the treatment of senile depression. Methods: according to the diagnostic standard of CCMD-3 and TCM depression, 97 cases of senile depression were randomly divided into traditional Chinese medicine group and Western medicine group, of which 4 cases were shedding (1 cases of Chinese medicine group, 3 cases in western medicine group), 53 cases of traditional Chinese medicine group and 40 cases in western medicine group after elimination. The therapeutic effect of two groups was recorded. Results: there was no significant difference between the two groups of Hamilton Depression Scale (HAMD), the self rating Depression Scale (SDS) score and TCM symptom score (P0.05). After 8 weeks of treatment, the TCM group HAMD, the SDS scale score and the TCM symptom score were superior to those in the western medicine group, the difference was statistically significant (P0.0 5) after 8 weeks of treatment, the total effective rate of Chinese medicine group was 94.3% higher than that of Western medicine group (75%), the difference was statistically significant (P0.05). The incidence of adverse reaction of Chinese medicine group was 9.4% lower than that of Western medicine group 30%, the difference was statistically significant (P0.05). Conclusion: Shuxin decoction is better than Sertraline Hydrochloride Tablets in the treatment of senile depression, and the safety is high.

【作者单位】：华北理工大学;煤炭总医院中西医结合诊治中心;
【基金】：煤炭总医院128人才计划项目资助(128人才G-2012-01)
【分类号】：R277.7

【相似文献】