自拟补肾益髓方治疗膝关节骨性关节炎（肝肾不足型）的临床研究

发布时间：2018-05-18 04:32

本文选题：膝关节骨性关节炎 + 中药汤剂　；参考：《长春中医药大学》2016年硕士论文

【摘要】：目的:观察自拟补肾益髓方治疗膝关节骨性关节炎(肝肾不足型)的临床疗效。方法:本课题遵循随机平行对照研究方法,对2015年1月至12月在长春中医药大学附属医院骨科门诊患者,选择符合该病的中西医诊断标准的患者120例,随机平行分为治疗组和对照组,每组60例。对照组选择的口服药物为金乌骨通胶囊。两组条件均衡:性别、年龄、病程、病情等差异无显著性意义(P0.05)。对照组:口服药物为金乌骨通胶囊,服用方法为每次1.5g,口服,每日3次,温开水送服,连服1月。治疗组:自拟补肾益髓方,水煎取汁150ml,早晚顿服,连服1月。整个课题过程安排2次访视,第1次访视时间为患者初入组时(即治疗第1天),按入组时间先后顺序分配给患者一个单独的药物编号,第2次访视时间则安排在患者入组后疗程结束时,分别对患者临床症状的改善程度进行评估,以评估该汤剂口服的安全性与有效性。结果:两组患者的治疗结果显示,对照组60例临床控制4例、显效28例、有效22例、无效6例,总体有效率为90.00%;治疗组60例临床控制6例、显效25例、有效25例、无效4例,总有效率为93.33%。经统计学分析,治疗组的总体疗效同对照组相当,且治疗组在疼痛方面的改善程度优于对照组。结论:治疗组的总体疗效同对照组相当,且治疗组在疼痛方面的改善程度优于对照组,值得临床推广。
[Abstract]:Objective: to observe the clinical effect of self-made prescription for tonifying kidney and tonifying marrow in the treatment of osteoarthritis of knee joint. Methods: according to the method of randomized parallel control study, 120 patients in orthopedic department of Changchun University of traditional Chinese Medicine from January to December 2015 were selected to meet the diagnostic criteria of traditional Chinese and Western medicine. They were randomly divided into treatment group (n = 60) and control group (n = 60). The oral drug of the control group was Jinwu Gutong capsule. There was no significant difference between the two groups in terms of sex, age, course of disease and disease condition (P 0.05). Control group: Jinwu Gutong capsule was taken orally, 1.5 g each time, 3 times a day, warm boiled water was given for 1 month. Treatment group: self-made tonifying kidney-tonifying pulp prescription, decoction 150 ml, morning and evening, take even for 1 month. During the whole course of the study, two visits were arranged. The first visit was made when the patient first entered the group (that is, on the first day of treatment), and was assigned a single drug number according to the time sequence of the first visit. The time of the second visit was arranged at the end of the course of treatment to evaluate the improvement of the clinical symptoms of the patients respectively in order to evaluate the safety and efficacy of the decoction. Results: the results of two groups showed that there were 60 cases of clinical control, 28 cases of remarkable effect, 22 cases of effective, 6 cases of ineffective, and 60 cases of clinical control of 6 cases, 25 cases of remarkable effect, 25 cases of effective and 4 cases of ineffectiveness in the treatment group, and the total effective rate was 90.005% in the treatment group, 60 cases of which were clinically controlled, 25 cases effective, 25 cases effective, 4 cases ineffective. The total effective rate was 93.33. Statistical analysis showed that the overall curative effect of the treatment group was similar to that of the control group, and the improvement of pain in the treatment group was better than that in the control group. Conclusion: the overall curative effect of the treatment group is equal to that of the control group, and the improvement of pain in the treatment group is better than that in the control group, which is worthy of clinical popularization.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R274.9

【相似文献】