温阳利水汤治疗慢性肾心综合征患者的临床疗效

发布时间：2018-05-19 08:05

本文选题：温阳利水汤 + 慢性肾心综合征　；参考：《中国老年学杂志》2017年09期

【摘要】：目的探讨温阳利水汤治疗慢性肾心综合征(CRCS)患者的临床疗效。方法 72例CRCS患者随机分为治疗组与对照组,对照组给予常规治疗;治疗组在常规治疗基础上加用温阳利水汤口服,疗程2个月;观察两组治疗前后中医证候积分变化、血清B型尿钠肽(BNP)、血肌酐(CRE)、尿素氮(BUN)的含量变化及治疗前后6 min步行试验和明尼苏达生活质量评分变化。结果(1)与治疗前比较,两组治疗后血清BNP、CRE及BUN水平均明显下降,且治疗组下降程度明显优于对照组(均P0.05)。(2)与治疗前比较,两组6 min步行距离均明显增加,明尼苏达生活质量评分均明显下降(P0.05);组间比较,治疗组明显优于对照组(P0.05)。(3)与治疗前比较,治疗组胸闷、气短、面肢浮肿、尿少、畏寒肢冷、疲倦乏力等症状均有所好转(P0.05),对照组无明显改善(P0.05);组间比较,治疗组明显优于对照组(P0.05)。结论温阳利水汤可有效改善CRCS患者的心、肾功能,提高其生活质量。
[Abstract]:Objective to investigate the clinical effect of Wenyang Lishui decoction on chronic renal heart syndrome (CRCS) patients. Methods Seventy-two patients with CRCS were randomly divided into treatment group and control group, the control group was given routine treatment, the treatment group was treated with Wenyang Lishui decoction orally for 2 months, and the changes of TCM syndromes integral before and after treatment were observed. The changes of serum B-type natriuretic peptide (BNPN), creatinine (creatinine), urea nitrogen bun (bun), 6 min walking test and Minnesota quality of life score before and after treatment were observed. Results (1) compared with before treatment, the serum levels of BNP-CRE and BUN in the two groups were significantly lower than those in the control group (P0.05, P < 0.05), and the walking distance of 6 min in the treatment group was significantly higher than that in the control group (P0.05, P < 0.05), and the walking distance between the two groups was significantly higher than that in the control group (P < 0.05). The scores of Minnesota quality of life were significantly lower than those of the control group (P 0.05), the treatment group was superior to the control group in terms of chest tightness, shortness of breath, edema of face limbs, low urine, cold limbs. The symptoms of fatigue and fatigue were all improved (P0.05), but the control group had no obvious improvement (P0.05), and the treatment group was obviously better than the control group (P 0.05). Conclusion Wenyang Lishui decoction can effectively improve the heart and kidney function of CRCS patients and improve their quality of life.
【作者单位】：北京市宣武中医医院;长春中医药大学附属医院;
【基金】：吉林省教育厅科技发展计划项目(吉教科合字[2012第81号])
【分类号】：R259

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