产妇宝煎剂加味治疗人流术后宫腔残留的临床观察

发布时间：2018-06-15 00:31

本文选题：产妇宝煎剂加味 + 人工流产术后宫腔残留　；参考：《河南中医药大学》2016年硕士论文

【摘要】：目的:观察益气化瘀法对人工流产术后宫腔残留患者的临床治疗效果,初步探讨产妇宝煎剂加味治疗宫腔残留的作用机理,为产妇宝煎剂加味的临床应用提供科学依据,指导临床工作。方法:纳入符合诊断标准的人工流产术后宫腔残留患者63例,随机分为2组:观察组32人,对照组31人。观察组给予中药“产妇宝煎剂加味”,每日2次,每次1袋(200ml),连服14天;对照组行清宫术,术后给予口服抗感染药物治疗3天(头孢地尼分散片,100mg/次,日3次)。观察两组阴道出血时间、宫腔残留物变化情况、血β-HCG值、子宫复旧情况的变化及人工流产术后首次月经复潮情况。结果:(1)治疗后两组总体疗效比较,观察组治愈25例,有效6例,无效1例,总有效率为96.88%,对照组治愈22例,有效6例,无效3例,总有效率为90.32%,两组总体疗效经统计分析无显著性差异(P0.05)。(2)治疗后观察组阴道出血时间为4.22±1.70天,对照组为3.58±1.26天,两组差异经统计学分析无意义(P0.05)。(3)治疗后观察组和对照组均有促进子宫复旧的作用,两组比较无统计学意义(P0.05)。(4)治疗后观察组和对照组血β-HCG值均明显降低,比较两组差异无统计学意义(P0.05)。(5)治疗后在宫腔残留物排出方面,观察组治愈率为87.50%,总有效率为96.88%,对照组治愈率为83.87%,总有效率为90.32%,两组比较无统计学意义(P0.05)。(6)月经复潮时间,观察组短于对照组,差异有统计学意义(P0.01)。两组经期均在正常范围内,观察组经期长于对照组,差异无统计学意义(P0.05)。两组月经量相比差异有统计学意义(P0.05)。结论:(1)气虚血瘀是人工流产术后宫腔残留的主要病机之一;(2)产妇宝煎剂加味对于人工流产术后宫腔残留患者可缩短阴道流血时间、促进宫腔残留组织排出、促进子宫复旧及有利于血β-HCG降低,与清宫比较无差异。(3)产妇宝煎剂加味与清宫相比,有利于月经恢复,可能与减轻子宫内膜基底层受损有关。
[Abstract]:Objective: to observe the clinical therapeutic effect of Yiqi Huayu method on residual uterine cavity patients after artificial abortion, and to explore the mechanism of treating uterine cavity residue with modified Maternal Bao decoction, so as to provide scientific basis for the clinical application of modified Maternal Medicine decoction. Direct clinical work. Methods: 63 patients with residual uterine cavity were randomly divided into two groups: observation group (n = 32) and control group (n = 31). The observation group was treated with "Maternal Bao decoction" twice a day for 14 days, while the control group was treated with antiseptic drugs for 3 days (cefdinil dispersible tablets 100 mg / d, 3 times a day). The changes of vaginal bleeding time, uterine cavity residue, serum 尾 -HCG, uterine recovery and the first menstrual resuscitation after induced abortion were observed in the two groups. Results compared with the control group, 25 cases were cured, 6 cases were effective, 1 case was ineffective, and the total effective rate was 96.88%. In the control group, 22 cases were cured, 6 cases were effective, and 3 cases were ineffective. The total effective rate was 90.320.The total curative effect of the two groups was not significantly different by statistical analysis (P 0.05. 0. 2) after treatment, the vaginal bleeding time of the observation group was 4.22 卤1.70 days, and that of the control group was 3.58 卤1.26 days, and that of the control group was 3.58 卤1.26 days. The difference between the two groups was statistically significant (P0.05U. Y3) after treatment, both the observation group and the control group had the effect of promoting the recovery of uterus, and the serum 尾 -HCG value of the observation group and the control group were significantly lower than that of the control group. There was no significant difference between the two groups in the discharge of residual matter in uterine cavity after treatment. The cure rate of the observation group was 87.50, the total effective rate was 96.888.The cure rate of the control group was 83.87 and the total effective rate was 90.32. There was no significant difference between the two groups in menstrual recovery time. The observation group was shorter than the control group, the difference was statistically significant (P 0.01). The menstrual period of the observation group was longer than that of the control group, and the difference was not statistically significant (P 0.05). There was significant difference in menstrual volume between the two groups (P 0.05). Conclusion (1) Qi deficiency and blood stasis is one of the main pathogenesis of residual uterine cavity after induced abortion. To promote uterine restoration and blood 尾 -HCG decrease, there is no difference between Qing Gong and Qing Gong. 3) compared with Qing Gong, it is beneficial to menstruation recovery, which may be related to reducing the damage of endometrial basal layer.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.9

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