王氏术黄调经合剂治疗脾肾两虚型月经过少临床研究

发布时间：2018-06-20 09:03

本文选题：月经过少 + 王氏术黄调经合剂　；参考：《山西中医学院》2016年硕士论文

【摘要】：目的观察王氏术黄调经合剂治疗脾肾两虚型月经过少的临床疗效,为临床应用提供理论支持和科学依据。方法将符合标准的80例患者按照随机数字表法分为治疗组和对照组各40例,采用单盲法分别给予王氏术黄调经合剂和夏氏健脾温肾汤治疗。两组均以一个月经周期为一个疗程,治疗三个疗程。观察患者治疗前后月经量的恢复情况,临床症状、体征的改善情况,子宫内膜、BBT的的变化情况及药物的副作用。结果1.临床总疗效比较:经过三个疗程的治疗,治疗组总有效率为97.5%,对照组总有效率为92.5%,两组临床总疗效比较P=0.049(P0.05),差异有统计学意义,治疗组优于对照组。2.月经量积分比较:两组治疗前比较P=0.812(P0.05),差异无统计学意义,具有齐同可比性。两组治疗后分别进行治疗前后比较P=0.000(P0.01),差异有统计学意义,说明两组药物均能使月经量增加。且两组治疗后比较P=0.017(P0.05),差异有统计学意义,说明治疗组对月经量的增加优于对照组。3.中医证候积分比较:两组治疗前比较P=0.957(P0.05),差异无统计学意义,具有齐同可比性。两组治疗后分别进行治疗前后比较P=0.000(P0.01),差异有统计学意义,说明两组药物均能使临床症状改善。且两组治疗后比较P=0.044(P0.05)差异有统计学意义,说明治疗组对临床症状的改善优于对照组。4.子宫内膜厚度比较:两组治疗前比较P=0.987(P0.05),差异无统计学意义,具有齐同可比性。两组治疗后分别进行治疗前后比较P=0.000(P0.01),差异有统计学意义,说明两组药物均能促进子宫内膜的增生和修复。两组治疗后比较,P=0.146(P0.05),差异无统计学意义,说明两组药物对子宫内膜的增生和修复作用相当。5.BBT:两组患者治疗前后基础体温均呈双相,说明两组对BBT影响不明显。6.安全性及不良反应:两组患者治疗前后均未出现任何的不良反应。结论1.两组均能通过增加月经量,改善临床症状及使子宫内膜增厚来达到治疗的目的。2.两组在增加子宫内膜厚度上无差异,但在增加月经量,改善临床症状及总疗效方面,服用王氏术黄调经合剂的治疗组疗效均优于服用夏氏健脾温肾汤的对照组。
[Abstract]:Objective to observe the clinical effect of Wang's zhuangtiaojing mixture in treating menorrhagia due to deficiency of spleen and kidney, and to provide theoretical support and scientific basis for clinical application. Methods according to the standard, 80 patients were randomly divided into treatment group (n = 40) and control group (n = 40). The two groups were treated with one menstrual cycle and three courses of treatment. The recovery of menstrual volume, improvement of clinical symptoms and signs, changes of BBT in endometrium and side effects of drugs were observed before and after treatment. Result 1. Comparison of the total clinical efficacy: after three courses of treatment, the total effective rate of the treatment group was 97.5 and the total effective rate of the control group was 92.5. The total clinical efficacy of the two groups was compared with that of the two groups. The difference was statistically significant, and the treatment group was better than the control group. Comparison of menstrual volume score: before treatment, there was no significant difference between the two groups. The difference between the two groups before and after treatment was statistically significant, indicating that both groups could increase the menstrual volume. The difference between the two groups after treatment was statistically significant, indicating that the increase of menstrual volume in the treatment group was better than that in the control group. 3. Comparison of TCM syndromes integral: two groups were compared before treatment, the difference was not statistically significant and comparable. The difference between the two groups before and after treatment was statistically significant, which indicated that the two groups could improve the clinical symptoms. The difference between the two groups after treatment was statistically significant, indicating that the improvement of clinical symptoms in the treatment group was better than that in the control group. 4. Comparison of endometrial thickness: there was no significant difference in endometrial thickness between the two groups before treatment. After treatment, the two groups were compared before and after treatment, the difference was statistically significant, indicating that the two groups of drugs can promote the proliferation and repair of endometrium. There was no significant difference between the two groups after treatment, indicating that the two groups had the same effect on endometrial hyperplasia and repair. 5. BBT: the basic body temperature of the two groups was biphasic before and after treatment, indicating that the two groups had no significant effect on BBT. 6. Safety and adverse reactions: there were no adverse reactions in both groups before and after treatment. Conclusion 1. Both groups were able to achieve treatment by increasing menstrual volume, improving clinical symptoms and thickening the endometrium. There was no difference between the two groups in increasing endometrial thickness, but in increasing menstrual volume, improving clinical symptoms and total curative effect, the curative effect of the treatment group taking Wang's Shuzhu Huang Tiaojing mixture was better than that of the control group taking Xia's Jianpi Wenshen decoction.
【学位授予单位】：山西中医学院
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.111

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