补肾活血汤联合针灸治疗老年痴呆临床研究

发布时间：2018-08-08 21:33

【摘要】：目的:观察补肾活血汤联合针灸治疗老年痴呆的临床疗效。方法:将2014年1月—2015年4月收治的56例老年痴呆患者随机分为治疗组30例和对照组26例。对照组给予多奈哌齐与尼莫地平联合用药,治疗组在对照组的基础上加用补肾活血汤联合针灸治疗。比较两组患者的临床疗效,观察两组患者治疗前后痴呆病理行为评定量表(BEHAVE-AD)评分、精神状态检查表(MMSE)评分、日常生活活动评分(ADI)、激越行为量表(CMAI)评分、个人和社会功能量表(PSP)评分、健康调查简表(SF-36)评分变化情况。结果:对照组有效率为53.9%,治疗组有效率为83.3%,两组患者临床疗效比较,差异具有统计学意义(P0.05)。两组患者治疗后BEHAVE-AD、MMSE、ADI、CMAI、PSP、SF-36评分优于治疗前,且治疗组优于对照组,差异均有统计学意义(P0.05)。对照组不良反应发生率为38.5%,治疗组不良反应发生率为10.0%,两组不良反应发生率比较,差异具有统计学意义(P0.05)。结论:补肾活血法联合针灸治疗老年痴呆临床疗效显著,可显著改善患者的临床症状。
[Abstract]:Objective: to observe the clinical effect of Bushen Huoxue decoction combined with Acupuncture and moxibustion on senile dementia. Methods: 56 patients with Alzheimer's disease from January 2014 to April 2015 were randomly divided into treatment group (n = 30) and control group (n = 26). The control group was treated with Donepezil and nimodipine, and the treatment group was treated with Bushen Huoxue decoction combined with acupuncture on the basis of the control group. The clinical efficacy of the two groups was compared, and the scores of BEHAVE-AD, (MMSE), (ADI), agitation behavior scale (CMAI) before and after treatment were observed. Changes in personal and Social function scale (PSP) and Health Survey Summary (SF-36) score. Results: the effective rate was 53.9 in the control group and 83.3 in the treatment group. The difference between the two groups was statistically significant (P0.05). After treatment, the scores of BEHAVE-ADMMSEI CMAI PSPSF-36 in the two groups were better than before, and the treatment group was better than the control group, the difference was statistically significant (P0.05). The incidence of adverse reactions was 38.5 in the control group and 10.0 in the treatment group. The difference between the two groups was statistically significant (P0.05). Conclusion: the therapy of tonifying kidney and activating blood circulation combined with acupuncture and moxibustion is effective in the treatment of senile dementia and can improve the clinical symptoms of senile dementia.
【作者单位】：湖北医药学院附属人民医院;
【基金】：国家自然科学基金青年基金资助课题(编号:30801506)
【分类号】：R277.7

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