醒脾益肾方治疗胡桃夹综合征的临床观察
发布时间：2018-08-14 09:54
【摘要】：目的：应用醒脾益肾方治疗胡桃夹综合征脾肾两虚证的患者,对比患者治疗前后的症状、体征及相关实验室指标变化,观察该方的临床疗效,为中医药治疗胡桃夹综合征提供临床指导。方法：选取30例西医诊断为胡桃夹综合征,且中医辨证为脾肾两虚证的患者,采用治疗前后自身对照的研究观察方法,应用醒脾益肾方治疗,总疗程为6个月。对比治疗前与治疗后患者中医证候积分、尿红细胞高倍镜下计数、24小时尿蛋白定量、腹主动脉和肠系膜上动脉夹角处的左外侧左肾静脉血管内径(mm)与肠系膜上动脉和腹主动脉夹角处的左侧肾静脉血管内径(mm)的比值等临床数据。结果：1.治疗6个月后中医证候积分的总有效率达86.7%。中医证候积分符合正态性,采用配对样本t检验,t=13.202,P0.01,有显著差异,具有统计学意义。2.尿红细胞高倍镜下计数、24小时尿蛋白定量值均符合正态性,治疗3个月、6个月后两组尿红细胞高倍镜下计数、24小时尿蛋白定量较治疗前均降低(P0.01),差异具有统计学意义。3.泌尿系彩超LRV内径比值符合正态性,治疗6个月后LRV内径比值明显低于用药前LRV内径比值(P0.01),差异具有统计学意义。结论：1应用醒脾益肾方可有效改善胡桃夹综合征(脾肾两虚)患者的中医症状。2应用醒脾益肾方可降低胡桃夹综合征(脾肾两虚)患者尿蛋白、尿潜血。3应用醒脾益肾方可在一定程度缓解左肾静脉受压。
[Abstract]:Objective: to observe the clinical effect of Xingpi Yishen prescription in treating the patients with deficiency of spleen and kidney in Nutcracker syndrome, comparing the symptoms, signs and related laboratory indexes before and after treatment. To provide clinical guidance for the treatment of nutcracker syndrome with traditional Chinese medicine. Methods: 30 cases of Nutcracker syndrome diagnosed by western medicine and syndrome differentiation of spleen and kidney deficiency in TCM were selected. The self-control study and observation before and after treatment were carried out, and the total course of treatment was 6 months. The scores of TCM syndromes before and after treatment were compared, and the urine red blood cells were counted under high power microscope to quantify 24 hours urine protein. The ratio of the diameter of left lateral renal vein (mm) at the angle between abdominal aorta and superior mesenteric artery to that of left renal vein (mm) at the angle of superior mesenteric artery and abdominal aorta. The result is 1: 1. After 6 months of treatment, the total effective rate of TCM syndromes integral was 86.7%. The integral of TCM syndromes accorded with normality, and the matched sample t test was used to test 13.202% P0.01.The difference was statistically significant. The quantitative values of urinary protein in 24 hours under high magnification microscope were in accordance with normality. After 3 months of treatment, the 24 hour urine protein in the two groups was lower than that before treatment (P0.01), the difference was statistically significant (P 0.01). The ratio of LRV diameter in urography was normal. After 6 months of treatment, the ratio of LRV diameter was significantly lower than that of LRV before treatment (P0.01), and the difference was statistically significant. Conclusion the application of "Xianpi Yishen decoction" to improve the symptoms of traditional Chinese medicine in the patients with nutcracker syndrome (deficiency of spleen and kidney). 2. The application of Qianpi Yishen decoction can reduce urine protein in patients with nutcracker syndrome (deficiency of spleen and kidney). Urine occult blood .3 was used to relieve the pressure of left renal vein to a certain extent.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5
本文编号：2182490
[Abstract]:Objective: to observe the clinical effect of Xingpi Yishen prescription in treating the patients with deficiency of spleen and kidney in Nutcracker syndrome, comparing the symptoms, signs and related laboratory indexes before and after treatment. To provide clinical guidance for the treatment of nutcracker syndrome with traditional Chinese medicine. Methods: 30 cases of Nutcracker syndrome diagnosed by western medicine and syndrome differentiation of spleen and kidney deficiency in TCM were selected. The self-control study and observation before and after treatment were carried out, and the total course of treatment was 6 months. The scores of TCM syndromes before and after treatment were compared, and the urine red blood cells were counted under high power microscope to quantify 24 hours urine protein. The ratio of the diameter of left lateral renal vein (mm) at the angle between abdominal aorta and superior mesenteric artery to that of left renal vein (mm) at the angle of superior mesenteric artery and abdominal aorta. The result is 1: 1. After 6 months of treatment, the total effective rate of TCM syndromes integral was 86.7%. The integral of TCM syndromes accorded with normality, and the matched sample t test was used to test 13.202% P0.01.The difference was statistically significant. The quantitative values of urinary protein in 24 hours under high magnification microscope were in accordance with normality. After 3 months of treatment, the 24 hour urine protein in the two groups was lower than that before treatment (P0.01), the difference was statistically significant (P 0.01). The ratio of LRV diameter in urography was normal. After 6 months of treatment, the ratio of LRV diameter was significantly lower than that of LRV before treatment (P0.01), and the difference was statistically significant. Conclusion the application of "Xianpi Yishen decoction" to improve the symptoms of traditional Chinese medicine in the patients with nutcracker syndrome (deficiency of spleen and kidney). 2. The application of Qianpi Yishen decoction can reduce urine protein in patients with nutcracker syndrome (deficiency of spleen and kidney). Urine occult blood .3 was used to relieve the pressure of left renal vein to a certain extent.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.5
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