中药熏蒸联合针灸治疗老年肾虚寒湿型强直性脊柱炎的疗效及对炎症因子的影响

发布时间：2018-08-23 20:02

【摘要】：目的探讨中药熏蒸联合针灸对老年肾虚寒湿型强直性脊柱炎(AS)临床症状及炎症因子的影响。方法老年肾虚寒湿型AS患者120例,按随机数字表法分为对照组、中药组、针灸组及中药针灸组各30例。对照组给予常规西药治疗,中药组给予常规西药联合中药熏蒸治疗,针灸组给予常规西药联合针灸治疗,中药针灸组给予常规西药联合中药熏蒸及针灸治疗,连续治疗3个疗程。评价并比较4组治疗后的临床疗效。观察并比较4组治疗前后指地距、枕墙距、晨僵时间、Sehober试验及腰背痛视觉模拟评分(VAS)。检测并比较4组治疗前后红细胞沉降率(ESR)以及血清C反应蛋白(CRP)、白细胞介素(IL)-23及巨噬细胞移动抑制因子(MIF)水平。结果治疗后,中药组、针灸组及中药针灸组总有效率均明显高于对照组,且中药针灸组明显高于中药组和针灸组(P0.05)。治疗后中药组、针灸组及中药针灸组指地距、枕墙距、晨僵时间及腰背痛VAS均明显低于对照组,且中药针灸组均明显低于中药组和针灸组,Sehober试验评分明显高于对照组(P0.05);治疗后且中药针灸组评分明显高于中药组和针灸组(均P0.05)。治疗后中药组、针灸组及中药针灸组ESR及血清CRP、IL-23、MIF水平均明显低于对照组,且中药针灸组明显低于中药组和针灸组(均P0.05)。结论中药熏蒸联合针灸治疗老年肾虚寒湿型AS临床疗效显著,能够明显改善患者临床症状,降低炎症因子水平。
[Abstract]:Objective to investigate the effect of Chinese medicine fumigation combined with acupuncture on the clinical symptoms and inflammatory factors of senile ankylosing spondylitis with kidney-deficiency cold and dampness type. Methods 120 elderly AS patients with kidney deficiency and cold dampness were randomly divided into control group, Chinese medicine group, acupuncture and moxibustion group and acupuncture and moxibustion group. The control group was treated with conventional western medicine, the traditional Chinese medicine group with traditional Chinese medicine fumigation, the acupuncture group with routine western medicine combined with acupuncture and moxibustion, and the traditional Chinese medicine acupuncture group with routine western medicine combined with traditional Chinese medicine fumigation and acupuncture treatment. Three consecutive courses of treatment. To evaluate and compare the clinical effect of 4 groups after treatment. Observe and compare the digital distance, occipital-wall distance, morning stiffness time and visual analogue score of low back pain (VAS).) before and after treatment in 4 groups. Erythrocyte sedimentation rate (ESR), serum C-reactive protein (CRP),) interleukin-23 (IL-23) and macrophage migration inhibitory factor (MIF) were measured and compared before and after treatment. Results after treatment, the total effective rate of TCM group, acupuncture group and acupuncture group were significantly higher than that of control group, and the total effective rate of TCM acupuncture group was significantly higher than that of traditional Chinese medicine group and acupuncture group (P0.05). After treatment, the VAS of TCM group, acupuncture group and traditional Chinese medicine acupuncture group were significantly lower than that of control group, such as the distance of ground, the distance of occipital wall, the time of morning stiffness and the VAS of low back pain. The score of Sehober test in acupuncture and moxibustion group was significantly higher than that in control group (P0.05), and the score of acupuncture and moxibustion group after treatment was significantly higher than that in traditional Chinese medicine group and acupuncture group (P0.05). After treatment, the levels of ESR and serum CRP,IL-23,MIF in TCM group, acupuncture group and TCM acupuncture group were significantly lower than those in control group, and the levels of serum CRP,IL-23,MIF in TCM acupuncture group were significantly lower than those in traditional Chinese medicine group and acupuncture group (P0.05). Conclusion Chinese herbal fumigation combined with acupuncture in the treatment of AS with kidney deficiency and cold dampness can significantly improve the clinical symptoms and reduce the level of inflammatory factors.
【作者单位】：遵义医学院附属医院针灸科;遵义医学院附属医院肾病风湿科;
【基金】：2014度遵义市科技局遵义医学院附属医院联合科技研发项目(遵义科合社字[2014]99号)
【分类号】：R246.1

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