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口糜方治疗复发性阿弗他溃疡脾虚积热证的临床观察

发布时间:2018-10-22 07:23
【摘要】:目的:口糜方治疗复发性阿弗他溃疡脾虚积热证的临床观察。方法:采用平行对照方法将患者随机分为A、B两组。A组予以口糜方治疗,B组予以康复新液治疗。共计纳入60例患者,每组各30例。将临床遴选到的60例符合脾虚积热证复发性阿佛他溃疡条件的患者随机分为两组,其中30例予口糜方(KMF)治疗,其余30例予康复新液(KFXY)治疗作为对照。疗程7天后观察患者溃疡大小、数目,黄色渗出,周围充血明显范围大,溃疡疼痛的评估(即VAS评分)以及中医证候积分。运用VAS评分及溃疡的复发率来评估病情的变化情况。两组结果的统计运用SPSS22.0统计分析软件并根据数据的具体情况选用相应的统计方法加以分析。结果:两组中在减轻患者溃疡大小、溃疡数目、周围充血明显范围大小以及VAS评分等方面均改善显著(P0.05);在溃疡大小、周围充血范围及VAS评分方面治疗组均显著地高于对照组(P0.05)。在中医证侯积分方面,两组患者治疗前无显著差异;干预后两组患者均较治疗前显著改善(P0.05)并且治疗组较对照组变化显著(P0.05)。干预结束12周后,再次对患者进行问卷调查来询问口腔溃疡是否复发。治疗组30例患者中有5例复发,而在对照组30例患者中有11例复发。结论:两种治疗复发性口腔溃疡的方法都明显改善了口腔溃疡的溃疡情况以及疼痛感,但是口糜方还能够显著改善患者的中医证候积分。同时口糜方还能够明显降低口腔溃疡的复发率,但是康复新液并没有这种效果。两种治疗方法均安全,无明显副作用。
[Abstract]:Objective: to observe the clinical effect of oral Mi recipe in treating recurrent aphthous ulcer with spleen deficiency and heat syndrome. Methods: the patients were randomly divided into two groups: group A was treated with oral Mi prescription and group B was treated with Kangfeng Xin liquid. A total of 60 patients were included, 30 in each group. Sixty clinically selected patients were randomly divided into two groups: 30 cases were treated with Mi Fang (KMF) and the other 30 cases were treated with Kangangxin solution (KFXY) as control group. After 7 days of treatment, the size, number, yellow exudation, obvious range of peripheral congestion, evaluation of ulcer pain (I. E. VAS score) and TCM syndromes score were observed. VAS score and ulcer recurrence rate were used to evaluate the state of the disease. The statistics of the two groups of results are analyzed by SPSS22.0 software and the corresponding statistical methods are selected according to the specific situation of the data. Results: the size of ulcer, the number of ulcers, the obvious range of peripheral congestion and the VAS score were significantly improved in both groups (P0.05), and the treatment group was significantly higher than the control group in ulcer size, peripheral hyperemia range and VAS score (P0.05). In TCM syndromes score, there was no significant difference between the two groups before treatment; after intervention, the two groups were significantly improved compared with before treatment (P0.05) and the treatment group than the control group significantly changed (P0.05). Twelve weeks after the intervention, a questionnaire survey was conducted to ask if the ulcer recurred. In the treatment group, 5 cases recurred out of 30 cases, while 11 cases in the control group. Conclusion: the two methods of treating recurrent oral ulcer can obviously improve the ulcer condition and the feeling of pain, but the oral Mi prescription can also improve the TCM syndromes score of the patients. At the same time Mi Fang can also significantly reduce the recurrence rate of oral ulcers, but the new solution does not have this effect. Both methods were safe and had no obvious side effects.
【学位授予单位】:南京中医药大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R276.8

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