林慧娟教授治疗高血压经验整理与挖掘

发布时间：2018-11-05 16:34

【摘要】：目的:应用“中医传承辅助平台(V2.5)”系统软件,挖掘整理林慧娟教授中医药治疗高血压病的临证组方用药规律,总结并探讨林慧娟教授高血压诊疗的学术思想与经验,以期为我们以后的临证诊疗工作提供更好的帮助与指导。方法:首先,收集、整理林慧娟教授2013年1月至2015年12月期间诊疗的高血压病例,并从中筛选出符合研究标准的高血压患者的首诊病例资料170份,录入“中医传承辅助平台(V2.5)”系统,利用该系统软件的频数统计、集成关联、规则分析、复杂系统熵聚类、改进的互信息法、无监督的熵层次聚类等数据挖掘方法,统计分析林老高血压诊疗的临证组方用药规律。其次,在上述分析的基础上进一步对林教授治疗高血压的诊疗思路与学术思想进行总结与探讨。结果:林慧娟教授治疗170例高血压患者所用中药种类共113味,常用药物有天麻、葛根、钩藤、黄连、白芍、生地黄、牛膝、山药、黄芪、龙骨、牡蛎等。所用中药药性在四气上以寒性、平性药入方较多,五味上多选择以甘味、苦味药入方,且选用中药归经以入肝、肾、心经为主。基于关联规则分析,得到出现频次≥51次的药对43个,3味及以上的药物组合14组,并在此基础上进一步分析出了药物组合间的关联规则。基于熵聚类方法,推演出应用中药的两两之间的关联度。基于复杂熵聚类分析,得到治疗高血压的核心药物组合4组。结论:林慧娟教授诊疗高血压将药物的药性理论与现代药理研究成果结合在一起,自拟组方,疗效可靠。诊疗中主要使用镇肝熄风,平肝潜阳,补益肝肾,清热养阴,活血化瘀类药物,常用降压3号方加减诊疗肝肾阴虚,肝阳上亢型高血压。
[Abstract]:Objective: using the system software of "traditional Chinese Medicine inheritance Assistance platform (V2.5)", to excavate and sort out professor Lin Huijuan's clinical prescription of TCM treatment of hypertension, summarize and discuss the academic thought and experience of Professor Lin Huijuan in the diagnosis and treatment of hypertension. With a view to our future clinical diagnosis and treatment to provide better help and guidance. Methods: first of all, we collected and sorted out the cases of hypertension diagnosed and treated by Professor Lin Huijuan from January 2013 to December 2015, and selected 170 first-diagnosis data of hypertension patients who met the research criteria. Input "traditional Chinese Medicine inheritance Assistance platform (V2.5)" system, using the system software frequency statistics, integrated association, rule analysis, complex system entropy clustering, improved mutual information method, unsupervised entropy hierarchical clustering and other data mining methods, Statistics and analysis of the clinical prescriptions of Lin Lao hypertension. Secondly, on the basis of the above analysis, the diagnosis and treatment ideas and academic thoughts of Professor Lin for hypertension are summarized and discussed. Results: professor Lin Huijuan treated 170 patients with hypertension with 113 kinds of traditional Chinese medicine, commonly used drugs such as Gastrodia elata, Pueraria lobata, Rhizoma Uncaria, Rhizoma Coptidis, Radix Paeoniae Alba, Radix Rehmanniae, Radix Achyranthes, yam, Astragalus, keel, oyster, etc. The traditional Chinese medicine used in the four qi to cold, flat drugs into the more, five flavors to choose sweet flavor, bitter medicine into the prescription, and the choice of traditional Chinese medicine to enter the liver, kidney, heart meridian. Based on association rule analysis, the combination of 43, 3 or more drugs with frequency 鈮，

本文编号：2312657