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针灸治疗脑出血急性期累积Meta分析

发布时间:2019-04-27 20:15
【摘要】:目的:利用累积Meta分析,系统评价针灸治疗脑出血急性期的有效性和可能存在的优越性。方法:检索Cochrane Library、Pub Med、CNKI等数据库及相关期刊和高校图书馆论文库,运用STATA 14.0进行累积Meta分析。结果:共纳入7篇文献,按照文献发表年限行累积Meta示针灸治疗脑出血急性期初次被证明有效是在2009年,OR=3.48,95%CI[1.59,7.62],按样本量大小为序行累积Meta分析示针灸治疗脑出血急性期的OR值基本稳定,精确性逐次增高。以上分析表明治疗组有效率优于对照组,两组疗效比较差异有统计学意义(P0.01)。Egger检验法证明发表偏倚可能性较小,敏感性分析示所有的研究点值均落在最终结果的95%CI中,说明本研究结果可靠。结论:针灸治疗脑出血急性期疗效肯定,但鉴于可供纳入研究文献较少,质量较低,尚需更多高质量的研究以验证。
[Abstract]:Objective: to evaluate the effectiveness and possible superiority of acupuncture and moxibustion in the treatment of acute cerebral hemorrhage by cumulative Meta analysis. Methods: Cochrane Library,Pub Med,CNKI and other databases, related journals and library of academic libraries were searched, and cumulative Meta analysis was carried out by STATA 14.0. Results: a total of 7 articles were included. According to the published years, cumulative Meta showed that acupuncture and moxibustion was first proved effective in the acute phase of intracerebral hemorrhage in 2009, OR=3.48,95%CI [1.59, 7.62], Cumulative Meta analysis according to the sample size showed that the OR value of acupuncture and moxibustion treatment in acute phase of intracerebral hemorrhage was basically stable and the accuracy increased gradually. The above analysis showed that the effective rate of the treatment group was better than that of the control group, and there was a statistically significant difference between the two groups (P0.01). Egger test showed that the possibility of publication bias was less than that of the control group. Sensitivity analysis showed that all the point values of the study were located in the 95%CI of the final results, which indicated that the results of this study were reliable. Conclusion: acupuncture and moxibustion is effective in the treatment of cerebral hemorrhage in acute stage, but more high-quality studies are needed to verify it in view of the few literatures and the lower quality of acupuncture and moxibustion in the treatment of intracerebral hemorrhage.
【作者单位】: 广州中医药大学针灸康复临床医学院;广州中医药大学第一附属医院;
【基金】:国家自然科学基金(81303069) 广州市科技重大专项计划项目(2014Y2-00120) 广东省科学技术项目(2014A020221094) 国家中医药管局中医学术流派传承工作室项目
【分类号】:R246.6

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