Y-STR基因座分型缺失分析
发布时间：2018-08-24 19:55
【摘要】：目的分析Y-STR基因座等位基因分型缺失数据,为法医学提供应用参考。方法收集浙江汉族4477名无关男性个体血样,自动工作站磁珠法提取DNA,Y-filer~(TM)试剂盒进行复合扩增,GeneMapper ID v3.2分析软件分析Y-STR数据,统计出现基因分型缺失的概率。结果在4477名无关个体的Y-STR数据中,有来自23种单倍型的26个样本Y-STR分型各有1个短片段基因座的基因分型缺失,而其它长片段基因座的分型均完全正常。基因分型缺失的发生频率为0.518%。结论Y-STR基因座分型缺失具有一定的发生率,在日常检案中应注意防止误判。
[Abstract]:Objective to analyze the data of allelic deletion of Y-STR locus and provide reference for forensic medicine. Methods 4477 unrelated male blood samples from Zhejiang Han nationality were collected and the DNA,Y-filer~ (TM) was extracted by magnetic bead method on an automatic workstation. The Y-STR data were analyzed by multiple amplification software GeneMapper ID v3.2, and the probability of genotyping deletion was counted. Results in the Y-STR data of 4477 unrelated individuals, 26 Y-STR genotypes from 23 haplotypes had one short fragment locus deletion, while the other long fragment loci were completely normal. The frequency of genotyping deletion was 0.518%. Conclusion deletion of Y-STR locus has a certain incidence, and we should pay attention to the prevention of misjudgment in routine examination.
【作者单位】： 浙江省公安厅刑侦总队;
【分类号】：D919
[Abstract]:Objective to analyze the data of allelic deletion of Y-STR locus and provide reference for forensic medicine. Methods 4477 unrelated male blood samples from Zhejiang Han nationality were collected and the DNA,Y-filer~ (TM) was extracted by magnetic bead method on an automatic workstation. The Y-STR data were analyzed by multiple amplification software GeneMapper ID v3.2, and the probability of genotyping deletion was counted. Results in the Y-STR data of 4477 unrelated individuals, 26 Y-STR genotypes from 23 haplotypes had one short fragment locus deletion, while the other long fragment loci were completely normal. The frequency of genotyping deletion was 0.518%. Conclusion deletion of Y-STR locus has a certain incidence, and we should pay attention to the prevention of misjudgment in routine examination.
【作者单位】： 浙江省公安厅刑侦总队;
【分类号】：D919
【相似文献】
相关期刊论文 前10条
1 徐隆昌;易少华;黄代新;杨庆恩;;DNA甲基化及其与个体年龄相关性研究[J];中国法医学杂志;2011年04期
2 郑绍军;李静;曾丽;赵彩云;;微小果核上人体脱落细胞DNA检验[J];川北医学院学报;2011年03期
3 韩莉莉;林赛梅;沈晓丽;林立芳;潘棱;唐海燕;胡洁;;21三体综合征鉴定分析1例[J];中国法医学杂志;2011年04期
4 韩淑毅;高洪梅;张茂修;郑燕;郏雁飞;丁卜同;汪运山;;济南汉族群体5个Y-SNP位点的多态性分析[J];法医学杂志;2011年03期
5 孟庆丽;于卫建;叶萍;王e，
本文编号：2201864
本文链接：https://www.wllwen.com/falvlunwen/fanzuizhian/2201864.html
