种子类中药炒制过程化学成分变化机制研究进展

发布时间：2018-05-17 04:05

本文选题：种子类中药 + 炮制　；参考：《中草药》2017年12期

【摘要】：中药炮制是我国独有的具有自主知识产权的一项传统制药技术,中药炮制研究的内容包括历史沿革、炮制工艺、质量标准和炮制机制研究,而阐明中药炮制过程中化学成分变化是中药炮制机制研究的核心内容。种子类中药素有"逢子必炒"之说,其理论基础得到了国内外很多研究机构的证实,对临床常用种子类中药炮制过程化学成分变化机制进行概述,总结种子类中药炒制过程化学成分变化的共性规律,发现种子类中药炒制过程中,化学成分发生了复杂的变化,既有量变也有质变,且成分变化有一定的共性规律,即一般发生分解反应,达到炒制增效、减毒的目的。"逢子必炒"具有一定的科学内涵,应在中医药理论指导下进一步研究阐明,进而指导临床合理应用。
[Abstract]:Traditional Chinese medicine processing is a traditional pharmaceutical technology with independent intellectual property rights. The contents of traditional Chinese medicine processing research include historical evolution, processing technology, quality standard and processing mechanism. The change of chemical composition in the process of TCM processing is the core of the study of TCM processing mechanism. Seed Chinese medicine is known as "stir-fry every seed". Its theoretical basis has been confirmed by many research institutions at home and abroad. The mechanism of chemical composition change in the processing process of traditional Chinese medicine of seed type commonly used in clinic is summarized. In this paper, we summarize the common law of chemical composition change in seed Chinese medicine, and find out that the chemical composition has complex changes, both quantitative and qualitative changes, and there are some common rules of composition change in the process of seed Chinese medicine frying. That is, the general decomposition reaction, to achieve the purpose of speculation to increase efficiency and reduce toxicity. " "every seed must be fried" has certain scientific connotation, which should be further studied and clarified under the guidance of traditional Chinese medicine theory to guide the rational application of clinical practice.
【作者单位】：南京中医药大学国家教育部中药炮制规范化及标准化工程研究中心;南京海昌中药集团有限公司;江苏省中医药研究院;江苏建康职业学院;中国药科大学;
【基金】：国家自然科学基金面上项目(81573603);国家自然科学基金青年基金项目(81603297) 国家中医药管理局公益性行业专项(201507002-2) 江苏省普通高校研究生科研创新计划项目(KYZZ16_0413) 江苏省临床药学科研课题“南京药学会-常州四药医院药学科研基金”项目(2015YX005)
【分类号】：R283.1

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