抗阻训练结合健步走对非酒精性脂肪肝干预效果的研究

发布时间：2018-04-20 21:20

本文选题：非酒精性脂肪肝 + 抗阻训练　；参考：《广州体育学院》2017年硕士论文

【摘要】：研究目的近年来,抗阻训练在减肥方面有一定的研究,非酒精性脂肪肝人群大部分伴随肥胖状态,有氧运动对脂肪肝的干预效果已有大量的研究,并取得良好效果。抗阻训练结合有氧运动共同干预性脂肪肝当前未见有研究,本研究通过制定12周规律、合理、个体化的抗阻训练结合健步走运动处方对非酒精性脂肪肝患者实施干预,观察分析非酒精性脂肪肝患者的身体形态、身体成分、肝功能、血脂和肝脏B超影像等的变化,探讨抗阻训练结合健步走运动对非酒精性脂肪肝的干预效果,以期望能为非酒精性脂肪肝的防治工作提供有效的依据。研究方法采用自愿报名参加的形式,在医学体检的基础上,通过问卷调查和肝脏B超筛选出符合脂肪肝诊断标准的非酒精性脂肪肝患者进行抗阻训练结合健步走运动干预。其中男性18名,女性10名,年龄在32岁-56岁之间,平均年龄45.82±7.55岁。12周的抗阻训练结合健步走运动后,将13名连续1周内不能达到3次运动次数的研究对象视为脱落,对其余15名研究对象数据进行分析。实验过程中进行四次健康教育讲座;在开始实验前和实验结束后相同实验条件下测试研究对象的各项指标,包括肝脏B超、身体形态指标、身体成分、肝功能和血脂等指标。数据分析采用SPSS17.0社会科学统计软件包完成,运动干预前后的比较采用配对样本T检验完成,P0.05为差异有统计学意义。实验结果1运动前后身体形态的变化经过12周的运动干预后,非酒精性脂肪肝患者形态指标均有非常明显的降低。其中体重、BMI、腰围、臀围、腰臀比、胸围、大腿围均呈现出非常显著性降低(P0.01);运动干预前BMI仅有3例(20%)在正常范围内,运动后增加到7例(46.6%);腰臀比2例(13.3%)运动后增加到4例(26.6%),运动干预前有5例(33.3%)腰臀比超过1.0,运动后降低到0例。2运动前后身体成分的变化经过12周的运动干预后,非酒精性脂肪肝患者脂肪百分比、内脏脂肪水平和去脂肪软体重、腹部脂肪厚度具有非常显著性差异(P0.05)。3运动前后肝功能的变化经过12周的运动干预后,非酒精性脂肪肝患者ALP、γ—GT、LDH、DBIL、IBIL、TBIL、TP、GLOB、ALT、AST均降低,其中GLOB的降低具有显著性差异(P0.05),ALT和AST具有非常显著性差异(P0.01),其他指标均无统计学意义(P0.05)。另外A/G、ALB、AST/ALT有所上升。4运动前后血脂的变化经过12周的运动干预后,非酒精性脂肪肝患者运动前后除ApoA1/ApoB均值上升外,TG、CHOL、HDL-C、LDL-C、ApoA1、ApoB等六项指标均值均降低,除TG的降低具有显著性差异外(P0.05),其他指标的降低均不具统计学意义(P0.05)。运动干预前TG异常有10例(66%),经12周运动干预后,下降为4例(26%),CHOL从运动干预前的7例(46%)下降为5例(33%),LDL-C从运动前的6例(40%)下降为4例(26%)。5运动前后脂肪肝程度和疗效的分析经过12周的运动训练后,非酒精性脂肪肝患者中,3例中度脂肪肝均降低到轻度脂肪肝;12例轻度脂肪肝中有8例变为无脂肪肝,7例仍为轻度脂肪肝,B超图像显示5例在同等级中程度减轻,其他2例B超声像图显示无改变。本实验非酒精性脂肪肝患者中,治愈率为53.3%,有效但无治愈率为40%,无效率为6.7%,总有效率为93.3%。研究结论1本研究制定的12周抗阻训练结合健步走运动方案,可有效的改善NAFLD患者的体重、腰围和腰臀比等身体形态指标。2本研究制定的12周抗阻训练结合健步走运动方案,可有效的改善NAFLD的体脂率、内脏脂肪含量和腹部脂肪厚度。3本研究制定的12周抗阻训练结合健步走运动方案,可以有效改善NAFLD患者的肝功能、血脂指标。4坚持进行本研究制定的12周抗阻训练结合健步走运动方案,可有效的治疗NAFLD,并可使大部分轻度NAFLD完全逆转。5本研究制定的抗阻训练结合健步走运动方案安全有效且容易重复,可作为防治非酒精性脂肪性肝病的一项重要、安全、有效的基础治疗措施,值得在社区、临床上推广使用。
[Abstract]:In recent years, anti resistance training has been studied in the field of weight loss. The majority of non alcoholic fatty liver groups are associated with obesity, and the effect of aerobic exercise on fatty liver has been studied, and good results have been achieved. There is no research on the combination of resistance training and aerobic exercise. Formulating 12 weeks regular, rational, individualized resistance training combined with walking exercise prescription for non-alcoholic fatty liver patients, observe and analyze the changes of body shape, body composition, liver function, blood lipid and liver B ultrasound in patients with non-alcoholic fatty liver, and explore the resistance training combined with walking exercise for non-alcoholic fatty liver. The effect of intervention is expected to provide an effective basis for the prevention and control of non-alcoholic fatty liver disease. The research method, on the basis of voluntary registration, is based on a questionnaire survey and the liver B ultrasound screening of non alcoholic fatty liver patients who are in line with the criteria of fatty liver diagnosis and carry out anti resistance training combined with walking exercise. Among them, 18 men and 10 women, aged between 32 years old and -56 years old, the average age of 45.82 + 7.55 years old and.12 weeks of resistance training combined with walking exercise, the subjects of 13 consecutive 1 weeks that could not reach 3 times of movement were regarded as falling off, and the data of the other 15 subjects were analyzed. Four health education was carried out during the experiment. The indexes of the subjects were tested under the same experimental conditions before and after the beginning of the experiment, including the indexes of liver B ultrasound, body shape index, body composition, liver function and blood lipid. The data analysis was completed by SPSS17.0 social science statistics software package, and the comparison before and after exercise intervention was completed by paired sample T test, P0.05 The results were statistically significant. Results 1 after 12 weeks of exercise after 12 weeks of exercise, the morphological indexes of nonalcoholic fatty liver patients were significantly reduced. The weight, BMI, waist circumference, hip circumference, waist to hip ratio, chest circumference, thigh circumference were significantly decreased (P0.01); before exercise intervention, only 3 cases (2) 0%) in the normal range, 7 cases (46.6%) were increased after exercise, 2 cases of waist hip ratio (13.3%) increased to 4 cases (26.6%), 5 (33.3%) waist to hip ratio before exercise intervention was more than 1, after exercise, the changes of body composition before and after.2 movement were after 12 weeks of exercise, the percentage of fat and visceral fat in nonalcoholic fatty liver patients. After 12 weeks of exercise after 12 weeks of exercise, the changes in liver function after.3 exercise were significantly different from those of non alcoholic fatty liver patients, such as ALP, gamma GT, LDH, DBIL, IBIL, TBIL, TP, GLOB, ALT, and AST. The difference (P0.01), the other indexes were not statistically significant (P0.05). In addition, the changes of blood lipid in A/G, ALB and AST/ALT were increased after 12 weeks of exercise after.4 exercise. The mean value of TG, CHOL, HDL-C, LDL-C, ApoA1, etc. decreased with the increase of the mean value of ApoA1/ApoB in non alcoholic fatty liver patients before and after exercise. The reduction of other indicators (P0.05) was not statistically significant (P0.05). Before exercise intervention, there were 10 cases (66%) of TG abnormality. After 12 weeks of exercise, 4 cases (26%), 7 cases (46%) before exercise intervention decreased to 5 (33%), LDL-C decreased from 6 (40%) before movement to 4 (26%) the degree of fatty liver and efficacy before and after.5 exercise. After 12 weeks of exercise training, 3 patients with nonalcoholic fatty liver were reduced to mild fatty liver, 8 in 12 mild fatty liver and 7 in mild fatty liver, 7 in mild fatty liver, 5 in the same grade, and 2 in the other 2. In patients with fatty liver, the cure rate is 53.3%, effective but no cure rate is 40%, inefficiency is 6.7%, the total effective rate is 93.3%. study conclusion 1 this study of 12 weeks resistance training combined with walking exercise program, can effectively improve the body weight of NAFLD patients, waist circumference and waist hip ratio body shape index.2 developed for 12 weeks resistance training knot It can effectively improve the body fat rate of NAFLD, the content of visceral fat and the thickness of abdominal fat, which can effectively improve the liver function of the patients with NAFLD, which can effectively improve the liver function of the patients with NAFLD, and the blood lipid index.4 persists in the 12 week resistance training combined with the walking exercise scheme, which can be carried out by this study. Effective treatment of NAFLD, and can make most of the mild NAFLD completely reversal of.5, the anti resistance training combined with walking exercise program is safe and effective and easy to repeat. It can be used as an important, safe and effective basic treatment for non-alcoholic fatty liver disease. It is worth to be used in the community.

【学位授予单位】：广州体育学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：G804.2

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