运动与骨内分泌系统研究进展

发布时间：2018-05-11 07:09

本文选题：运动生物化学 + 骨钙素　；参考：《体育学刊》2017年03期

【摘要】：对运动与骨内分泌系统研究进行综合评述。骨作为新型的内分泌器官,具有内分泌功能。目前研究的重点主要是:骨钙素(OCN)和成纤维细胞生长因子23(FGF23)。其中OCN经过羧化后形成u OCN,再作用于脂肪细胞和胰岛,以此调节瘦素、脂联素、胰岛素的分泌,最终作用于骨,形成反馈性回路,进而调控能量代谢。而运动可能通过调节骨内分泌系统进而影响骨代谢,且不同方式运动对骨内分泌的调节不同,尤其是内分泌本质上是寻求内环境的稳定性,短时间或一次性运动对机体意义不大;当进行长期运动时,在调节骨结构的同时可显著影响相应因子,进而稳定骨内分泌系统。这为运动改善骨及其机体代谢的分子生物学机制提供了新的思路。
[Abstract]:The research on exercise and bone endocrine system was reviewed. As a new endocrine organ, bone has endocrine function. At present, the focus of this study is osteocalcin (OCN) and fibroblast growth factor 23 FGF23 (FGF23). After carboxylation, OCN forms u _ (OC), and then acts on adipocytes and islets to regulate the secretion of leptin, adiponectin and insulin, and finally to act on bone, form feedback circuit, and then regulate energy metabolism. Exercise may affect bone metabolism by regulating the bone endocrine system, and the regulation of bone endocrine is different in different ways, especially that endocrine essentially seeks the stability of internal environment. The short-term or one-off exercise is of little significance to the body, and when the long-term exercise is carried out, the bone structure can be regulated and the corresponding factors can be significantly affected, and then the bone endocrine system can be stabilized. This provides a new idea for the molecular biological mechanism of improving the metabolism of bone and body by exercise.
【作者单位】：华东师范大学体育与健康学院;华东师范大学青少年健康评价与运动干预教育部重点实验室;
【基金】：华东师范大学研究生科研创新实践资助项目(40600-511232-16203/013/086)
【分类号】：G804.7

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