抗菌消费品中纳米银含量调查及银的健康风险评价

发布时间：2018-05-03 11:21

本文选题：抗菌消费品 + AgNP　；参考：《生态毒理学报》2016年05期

【摘要】：纳米银(Ag NP)因具有良好的抗菌特性被广泛应用于日常消费品中,人体主要通过皮肤接触或口服等方式暴露于Ag NP。为了评价这些抗菌消费品中银对成人的非致癌暴露风险,对市面10种日常抗菌消费品中Ag NP和总银含量进行了调查,并采用美国环保局推荐的皮肤和口部暴露途径的健康风险评估模型来评价含银抗菌消费品引起的皮肤及口部非致癌暴露风险。调查结果表明:4种液态抗菌消费品中检测出Ag NP,含量为0.79~57.89 mg·L~(-1),占其总银含量的8.8%~99.1%。其他厂家标注含有Ag NP的抗菌消费品中则未检测出Ag NP。风险评价结果显示,大多数抗菌消费品的银风险熵为3.6×10-4~6.8×10-1,其中经皮肤暴露的银非致癌风险熵为1.0×10-3~6.8×10-1,经口暴露的银风险熵为3.6×10-4~6.0×10-3,对人体健康不会产生显著风险;然而,其中1种抗菌消费品中银的风险熵上限为0.86,接近于1,存在潜在的非致癌风险。
[Abstract]:Nano-silver silver NPs are widely used in consumer goods because of their good antibacterial properties. The human body is exposed to Ag NPs mainly through skin contact or oral administration. In order to evaluate the non-carcinogenic exposure risk of silver in these antibacterial consumer products to adults, the contents of Ag NP and total silver in 10 kinds of daily antibacterial consumer products were investigated. The health risk assessment model of skin and mouth exposure pathway recommended by USEPA was used to evaluate the non-carcinogenic exposure risk of skin and mouth caused by antimicrobial consumer products containing silver. The results showed that Ag NPs were detected in 4 kinds of liquid antimicrobial consumables, the content of Ag NPs was 0.79 ~ 57.89 mg / L ~ (-1), accounting for 8.8% ~ 99.1% of the total silver content. Other manufacturers labeled antibacterial consumer products containing Ag NP did not detect Ag NPs. The results of risk assessment showed that the silver risk entropy of most antimicrobial consumer products was 3.6 脳 10-46.8 脳 10-1, of which the non-carcinogenic risk entropy of silver exposed to skin was 1.0 脳 10-3 + 6.8 脳 10-1, and that of oral exposure was 3.6 脳 10-4 + 6.0 脳 10-3, which did not pose a significant risk to human health. The upper limit of risk entropy of silver in one kind of antimicrobial consumer goods is 0.86, which is close to 1.There is a potential non-carcinogenic risk.
【作者单位】：苏州科技大学环境科学与工程学院;中国科学院南京土壤研究所土壤环境与污染修复重点实验室;
【基金】：国家自然科学基金重点项目(41430752);国家自然科学基金项目(31570515) 江苏省自然科学基金项目(BK20131041) 苏州市科技支撑计划项目(SS201421,SS201523) 江苏高校水处理技术与材料协同创新项目苏州市环保科技项目(2015-3)
【分类号】：X820.4;X503.1

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