骨形态发生蛋白2型受体基因在肺动脉高压发病机制中的研究进展

发布时间：2018-01-22 17:51

  本文关键词： 肺动脉高压 肺毛细血管楔压 平均肺动脉压 骨形态发生蛋白 肺血管阻力 PASMC 压力异常 漂浮导管 Smad 发病机制 　出处：《中华高血压杂志》2017年05期 　论文类型：期刊论文

【摘要】：正肺动脉高压(pulmonary arterial hypertension,PAH)是一种罕见的以肺末梢小动脉进行性重构、肺动脉内压力异常升高为特征的临床疾病~([1])。PAH诊断标准为静息状态下右心漂浮导管(right-heart catheterization,RHC)测定平均肺动脉压(mean pressure of pulmonary artery,mPAP)≥25mm Hg(1mm Hg=0.133kPa),肺毛细血管楔压(pulmonary capillary wedge pressure,PCWP)≤15 mm Hg,肺血管阻力
[Abstract]:Pulmonary arterial hypertensioning (PAH) is a rare progressive remodeling of pulmonary terminal arterioles. Clinical diseases characterized by abnormal elevated pressure in the pulmonary artery (. [1. The diagnostic criteria for PAH were right heart catheterization under resting condition. Mean pressure of pulmonary artery. MPAP 鈮，

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