转基因植物生产疫苗和药物的研发进展

发布时间：2018-07-11 13:25

本文选题：植物生物反应器 + 疫苗　；参考：《生物技术通报》2017年09期

【摘要】：与传统的生产方式相比,以转基因植物作为生物反应器生产药用蛋白和疫苗,被认为是成本低廉、安全便捷的技术途径。目前,若干以转基因植物生产的药用蛋白已通过行政审批准予上市,一批转基因植物表达的人用或畜禽用疫苗也进入临床试验。综述了转基因植物生产疫苗和药用蛋白的研发进展与代表性案例,讨论了目前面临的问题与挑战,展望了未来技术发展方向。
[Abstract]:Compared with the traditional mode of production, using transgenic plants as a bioreactor to produce pharmaceutical proteins and vaccines is considered to be a low-cost, safe and convenient technical approach. At present, a number of medicinal proteins produced by transgenic plants have been approved to go on the market through administrative examination and approval, and a batch of vaccines expressed by transgenic plants for human use or livestock and poultry have also entered clinical trials. This paper reviews the research and development progress and representative cases of transgenic plant vaccine and medicinal protein, discusses the current problems and challenges, and looks forward to the future development of technology.
【作者单位】：中国农业科学院科技管理局;
【分类号】：Q819

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