乳腺癌患者血亲亲属对遗传咨询和基因检测意愿的调查
发布时间：2018-10-19 15:51
【摘要】：目的分析乳腺癌患者血亲亲属对遗传咨询和基因检测的了解和接受意愿。方法 992例乳腺癌患者的血亲亲属配合完成调查表,根据年龄、家庭收入、学历及肿瘤家族病史对数据进行建表分类及统计分析。结果参与完成调查的乳腺癌血亲亲属大多数对遗传咨询和基因检测不了解,但经简单宣教,大多数受调者愿意接受遗传咨询并参与风险评估、筛查。79.8%的受调者愿意接受基因检测,62.3%的受调者愿意进一步参与基因检测相关流程。大多数受调者能接受价格便宜的基因初筛,仅37.9%的受调者能接受价格较高的基因检测。假设基因检测阳性,大多数受调者愿意通过密切随访筛查进行预防,31.3%的受调者愿意选择预防性手术或药物。尽管告知检测结果保密,仍有32.9%的受调者担心不利影响。结论大多数乳腺癌患者的血亲亲属不了解但有明显意愿接受遗传咨询和基因检测,对乳腺癌遗传特点的误解、费用和受歧视的担忧是受调者接受遗传咨询、基因检测和相关预防筛查的主要障碍。
[Abstract]:Objective to analyze the understanding and acceptance of genetic counseling and genetic detection among relatives of breast cancer patients. Methods 992 patients with breast cancer were investigated by blood relatives. The data were classified and statistically analyzed according to age, family income, educational background and family history. Results most of the relatives of breast cancer who completed the survey did not know about genetic counseling and genetic testing. However, after simple education, most of the respondents were willing to receive genetic advice and participate in risk assessment. 79.8% of the subjects were willing to be tested and 62.3% were willing to participate in the process of gene testing. Most of the subjects were able to accept the initial screening of cheap genes, while only 37.9% of the subjects were able to accept the higher price of genetic tests. Assuming positive gene test, most of the subjects were willing to undergo close follow-up screening for prevention, and 31.3% of the subjects preferred preventive surgery or medication. Although the results were kept confidential, 32.9% of the respondents were worried about the adverse effects. Conclusion most of the relatives of breast cancer patients do not understand but have a clear willingness to accept genetic counseling and genetic testing. The misunderstandings about genetic characteristics of breast cancer, the cost and the fear of discrimination is that the adjuster receives genetic counseling. Major barriers to genetic testing and related preventive screening.
【作者单位】： 同济大学附属第一妇婴保健院乳腺外科;
【基金】：上海市卫生局青年科研项目(20134Y094) 上海市科委西医引导类项目(15411964800)~~
【分类号】：R737.9
，
本文编号：2281596
[Abstract]:Objective to analyze the understanding and acceptance of genetic counseling and genetic detection among relatives of breast cancer patients. Methods 992 patients with breast cancer were investigated by blood relatives. The data were classified and statistically analyzed according to age, family income, educational background and family history. Results most of the relatives of breast cancer who completed the survey did not know about genetic counseling and genetic testing. However, after simple education, most of the respondents were willing to receive genetic advice and participate in risk assessment. 79.8% of the subjects were willing to be tested and 62.3% were willing to participate in the process of gene testing. Most of the subjects were able to accept the initial screening of cheap genes, while only 37.9% of the subjects were able to accept the higher price of genetic tests. Assuming positive gene test, most of the subjects were willing to undergo close follow-up screening for prevention, and 31.3% of the subjects preferred preventive surgery or medication. Although the results were kept confidential, 32.9% of the respondents were worried about the adverse effects. Conclusion most of the relatives of breast cancer patients do not understand but have a clear willingness to accept genetic counseling and genetic testing. The misunderstandings about genetic characteristics of breast cancer, the cost and the fear of discrimination is that the adjuster receives genetic counseling. Major barriers to genetic testing and related preventive screening.
【作者单位】： 同济大学附属第一妇婴保健院乳腺外科;
【基金】：上海市卫生局青年科研项目(20134Y094) 上海市科委西医引导类项目(15411964800)~~
【分类号】：R737.9
，
本文编号：2281596
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