3种有机磷农药对水生生物的乙酰胆碱酯酶抑制效应的物种敏感度分析初探

发布时间：2019-04-20 12:37

【摘要】：通过筛选敌敌畏、马拉硫磷和对硫磷3种有机磷农药对水生生物的急性毒性数据和乙酰胆碱酯酶抑制效应数据,构建物种敏感度分布曲线进行了比较分析。结果表明,敌敌畏对水生生物的急性毒性和乙酰胆碱酯酶抑制效应的大小顺序为:酶体内抑制效应酶体外抑制效应急性毒性;马拉硫磷和对硫磷的乙酰胆碱酯酶抑制效应数据不足但趋势相似,顺序为:酶体内抑制效应急性毒性酶体外抑制效应。敌敌畏的急性毒性和酶体外抑制效应的5%危害浓度(HC5)分别为2.07μg·L~(-1)和1.53μg·L~(-1),两者相差1.4倍。在水质基准推导中,乙酰胆碱酯酶抑制效应数据对有机磷农药的水生生物基准具有重要的参考价值。
[Abstract]:By screening the data of acute toxicity of dichlorvos malathion and parathion to aquatic organisms and the inhibitory effect of acetylcholinesterase (ache) on aquatic organisms the species sensitivity distribution curves were compared and analyzed. The results showed that the acute toxicity of dichlorvos to aquatic organisms and the inhibitory effect of acetylcholinesterase (ache) on aquatic organisms were in the following order: the in vivo inhibitory effect of DDVP and the acute toxicity of in vitro inhibitory effect of DDVP; The data of acetylcholinesterase inhibitory effect of malathion and parathion were insufficient but the trend was similar. The order of inhibition effect in vivo was as follows: acute toxicity enzyme inhibitory effect in vitro. The 5% hazard concentration (HC5) of dichlorvos in acute toxicity and enzyme inhibition in vitro were 2.07 渭 g 路L ~ (- 1) and 1.53 渭 g 路L ~ (- 1), respectively, and the difference was 1.4 times. In the derivation of water quality benchmark, the data of inhibition effect of acetylcholinesterase have important reference value to the aquatic biological standard of organophosphorus pesticides.
【作者单位】：桂林理工大学环境科学与工程学院;中国环境科学研究院环境基准与风险评估国家重点实验室国家环境保护化学品生态效应与风险评估重点实验室;
【基金】：国家水体污染控制与治理科技重大专项(2012ZX07501-003) 科技基础性工作专项(2014FY120600) 国家自然科学基金(51268008,21407139)
【分类号】：X171.5;X592

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