居民经手口途径摄入含PAHs颗粒物的致癌风险评价

发布时间：2018-02-24 05:45

  本文关键词： 手口途径 污染颗粒物 PAHs 概率风险模型 蒙特卡罗模拟 致癌风险　出处：《环境科学》2017年10期 　论文类型：期刊论文

【摘要】：为评价居民经手口途径暴露于被PAHs污染室外土壤和室内灰尘颗粒的致癌风险以及与之相关各个参数的重要程度,本文构建了经手口途径暴露于这两种颗粒物的概率风险模型,运用蒙特卡罗模拟方法评价了居民的致癌风险,探究了主要的风险来源及关键的暴露参数.结果表明,幼儿、儿童和青少年所承受的风险较大;婴儿、成年人和老年人较小.婴儿致癌风险超过10~(-6)的概率为2%左右;幼儿和青少年超过10~(-6)的概率在5%左右,但不超过10~(-4);儿童超过10~(-6)的概率在15%左右,有0.1%左右的概率超过10~(-4);成年人和老年人超过10~(-6)的概率分别在1%和0.1%左右.室内灰尘颗粒是主要的风险来源,占91%左右;室内硬表面灰尘是室内致癌风险的主要来源,占65%左右.与致癌风险相关性最大的因素为:手口途径发生的频次(FQ)、灰尘颗粒中PAHs的等效斜率(PEFj)、灰尘在室内硬表面的含量(DSLHS)、颗粒物从手掌皮肤表面到口腔的转移率(SE)和灰尘在室内软表面的含量(DSLSS).
[Abstract]:Through oral route for the evaluation of residents exposed to PAHs contaminated soil and outdoor indoor dust particles of carcinogenic risk and related parameters of importance, this paper constructs the risk probability model through oral route exposed to these two kinds of particles, using Monte Carlo evaluation of the residents carcinogenic risk simulation method, to explore the main risk the source and key exposure parameters. The results showed that infants, children and adolescents suffer greater risk; infants, adults and the elderly are smaller. Baby cancer risk more than 10~ (-6) the probability is about 2%; children and adolescents over 10~ (-6) the probability of around 5%, but not more than 10~ (-4) children; more than 10~ (-6) in the probability of about 15%, about 0.1% of the probability of more than 10~ (-4); adults and the elderly over 10~ (-6) probability respectively in 1% and 0.1%. The indoor dust particles is the main risk to 婧，

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