消炎痛生产废水处理工艺设计及运行控制研究

发布时间：2018-07-17 15:57

【摘要】：消炎痛,又称为吲哚美辛,英文名为:Indomethacin,是一种具有抑制环氧酶的作用致使前列腺素的合成减少以达到抗炎、镇痛、解热作用的非甾体抗炎药,分子式:C19H16ClnO4,在其重氮、酰化、合环、精致等生产过程中,产生了大量制药废水,该废水成分复杂,处理难度大。本课题目的是针对石家庄经济技术开发区某企业消炎痛生产废水浓度高,色度深、处理难度大的特点,在经过中试的基础上,进行了工程工艺设计和运行控制研究,希望对消炎痛废水的处理提供一些参考。预处理实验表明,采用PAC(聚合氯化铝)、PAM(聚丙烯酰胺)作为最佳混凝剂,最佳投加量分别为200 mg/L和0.8 mg/L,进水指标COD5000~5500 mg/L,SS2500-3000 mg/L,出水COD、SS为3500-3850 mg/L和300~360 mg/L,COD、SS去除率为30%和88%,为后续处理打下良好基础。通过方案对比,确定“均质调节—预曝气池—混凝沉淀—ABR—SBR—BAF”为处理工艺方案。经过调试与稳定运行数据分析,工程日处理废水1000 m3/d,处理后的COD、氨氮去除效率可达99%,达到要求的设计排放标准,运行效果良好,出水水质满足石家庄经济技术开发区污水处理厂污水接纳协议标准。项目占地面积为2474 m2,总投资2043.11万元,年运行费用为764.85万元/a,运行成本为25.495元/吨。研究结果表明,论文提出的组合工艺对消炎痛废水处理经济有效,技术可行。
[Abstract]:Indomethacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug with an inhibitory effect on cyclooxygenase that reduces the synthesis of prostaglandins to achieve anti-inflammatory, analgesic, and antipyretic effects, with the molecular formula: C19H16ClnO4, in its diazo, acylation, and ring. A large amount of pharmaceutical wastewater is produced in the process of delicate production, which is difficult to treat because of its complex composition. In view of the characteristics of high concentration, deep chroma and difficulty in treatment of indomethacin wastewater in a certain enterprise in Shijiazhuang Economic and technological Development Zone, the engineering process design and operation control are studied on the basis of pilot test. It is hoped to provide some references for the treatment of indomethacin wastewater. The pretreatment experiment showed that PAC (polyaluminum chloride) PAM (polyacrylamide) was used as the best coagulant. The optimal dosages are 200 mg / L and 0.8 mg / L, respectively. The influent index COD5000 ~ 5500 mg / L is 2500-3000 mg / L, the effluent CODSS is 3500-3850 mg / L and the removal rate of 300-360 mg / L / L CODSS is 30% and 88% respectively, which lays a good foundation for the follow-up treatment. The homogenization adjustment-pre-aeration tank-coagulation sedimentation-ABR-SBR-BAF was selected as the process plan. After debugging and stable operation data analysis, the waste water is treated by 1000 m3 / d per day. After treatment, the removal efficiency of ammonia nitrogen can reach 99%, which meets the required design discharge standard, and the operation effect is good. The effluent quality meets the agreement standard of sewage treatment plant in Shijiazhuang Economic and technological Development Zone. The area of the project is 2474 m2, the total investment is 20.4311 million yuan, the annual operating cost is 7.6485 million yuan / a, and the operating cost is 25.495 yuan / ton. The results show that the combined process proposed in this paper is economical, effective and feasible for indomethacin wastewater treatment.
【学位授予单位】：河北科技大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：X787

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