补肾调周法配合耳压治疗多囊卵巢综合征的临床研究

发布时间：2017-12-28 01:36

  本文关键词：补肾调周法配合耳压治疗多囊卵巢综合征的临床研究　出处：《南京中医药大学》2017年硕士论文　论文类型：学位论文

  更多相关文章： 调周法 耳穴 多囊卵巢综合征

【摘要】：目的:本研究运用补肾调周法配合耳压治疗多囊卵巢综合征(PCOS)患者的临床研究,通过比较治疗组及对照组治疗前后患者的月经周期、多毛、痤疮等临床症状的改善情况,肥胖指数(BMI)、基础体温(BBT)、基础血性激素及妇科B超的变化情况。评价补肾调周法配合耳压的疗效,探讨耳压对补肾调周法治疗痰湿瘀阻型PC0S的潜在协同效用。方法:本研究选择2015年02月至2017年02月就诊于江苏省中医院妇科门诊的多囊卵巢综合征患者共60例,按照随机原则分为两组:(1)治疗组:30例,予补肾调周法及耳压配合口服达英-35治疗;(2)对照组:30例,予耳压配合口服达英-35治疗。三个月经周期为一个疗程,观察两个疗程治疗前后患者的月经周期、多毛、痤疮等临床症状的改善情况,肥胖指数(BMI)、基础体温(BBT)、基础血性激素及妇科B超的变化情况。结果:综合疗效方面,治疗组总有效率为83.33%,对照组总有效率为73.33%。两组在临床表现及中医征候、BBT、BMI、基础血性激素水平及B超方面治疗前后均有改善(P0.05)。组间比较:临床症状改善、BMI、T、DHEAS、SHBG下降率及B超情况改善方面治疗组优于对照组(P0.05),BBT改善情况及LH与LH/FSH下降率方面治疗组与对照组组间差异无统计学意义(P0.05)。结论:本研究结合辨证论治的原则与月经周期的规律,以针药结合的方法,证实了调周法配合耳压可明显改善痰瘀互结型PC0S患者的临床症状,疗效确切,且临床无明显副作用。其作用机制可能是通过降低血清中睾酮和游离睾酮的浓度,降低血清促黄体生成素水平,从而调节内分泌水平来实现,可推广运用于临床,且可以为临床提供有效的循证医学证据。
[Abstract]:Objective: To study the application of tkrpm combined with ear pressure treatment of polycystic ovary syndrome (PCOS) patients with clinical research, through the comparison of treatment group and control to improve the patient's menstrual cycle, hirsutism and acne and other clinical symptoms before and after treatment, obesity index (BMI), basal body temperature (BBT), the change of foundation sex hormone and gynecological ultrasound. To evaluate the effect of Tonifying the kidney and regulating the week with the ear pressure, and to explore the potential synergistic effect of the ear pressure on the treatment of phlegm dampness and stasis type PC0S by the method of Tonifying the kidney and regulating the perimeter. Methods: a total of 60 cases of polycystic ovarian syndrome were selected in this study from 2015 02 to 2017 02 months in Jiangsu Province Traditional Chinese Medicine Hospital from gynecological outpatient clinic, were randomly divided into two groups: (1) the treatment group: 30 cases, treated with the method of invigorating kidney and ear pressure combined with oral treatment with -35; (2) control group: in 30 cases, treated with oral -35 treatment with ear pressure. The three menstrual cycle is a course of treatment. We observed the improvement of clinical symptoms, such as menstrual cycle, hairy and acne, and the changes of obesity index (BMI), basal body temperature (BBT), basal blood hormone and gynecological ultrasound before and after two courses of treatment. Results: the total effective rate of the treatment group was 83.33%, and the total effective rate of the control group was 73.33%. The two groups before and after treatment in the clinical manifestations and syndrome, BBT, BMI, sex hormone levels and ultrasound were improved (P0.05). Comparison between groups: the improvement of clinical symptoms, BMI, T, DHEAS, SHBG and the improvement of B-mode ultrasound were better in the treatment group than in the control group (P0.05). There was no significant difference in the improvement of BBT and the decrease rate of LH and LH/FSH between the treatment group and the control group (P0.05). Conclusion: combined with the principle of syndrome differentiation and menstrual cycle, this study confirms that the combination of acupuncture and medicine can significantly improve the clinical symptoms of patients with phlegm and blood stasis type PC0S, and has no obvious side effects. The mechanism may be achieved by decreasing the concentration of testosterone and free testosterone in serum, decreasing serum luteinizing hormone level and regulating endocrine level, which can be widely applied in clinical practice, and can provide effective evidence-based medical evidence for clinical practice.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R271.9

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