新疆中青年缺血性卒中脑血管狭窄相关因素的研究

发布时间：2017-12-28 07:32

本文关键词：新疆中青年缺血性卒中脑血管狭窄相关因素的研究　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨中青年缺血性卒中脑血管狭窄的相关因素,及维、汉中青年缺血性卒中脑血管狭窄相关因素及分布的差异性。方法:回顾性收集中青年缺血性卒中患者520例,根据DSA或头颈部CTA检查分为血管狭窄组256例(男176例,女80例)和无血管狭窄组264例(男200例,女64例),根据民族将血管狭窄组分为:维吾尔族组72例(男52例,女20例),汉族组184例(男124例,女60例),收集患者临床资料,进行比较。结果:(1)与汉族组比较,维吾尔族组前循环血管病变率显著升高,后循环、前-后循环联合病变率显著降低(P0.05)。(2)两组均以颅内血管病变多见,与汉族族比较,维吾尔族组颅内血管狭窄或闭塞率明显升高,颅外血管狭窄或闭塞率、颅内-外联合病变率降低(均P0.05)。(3)与汉族族比较,维吾尔族组颅外血管轻、中度狭窄的比率较高,重度狭窄、闭塞率较低(P0.05)。(4)与汉族组比较,维吾尔族组IVA、MCA、PCA血管病变率降低,ACA、BA、I-ICA病变率升高(P0.05)。(5)与汉族组比较,维吾尔族组HHcy)、BMI≥25kg/m2、高血压发生率增高(P0.05),吸烟、饮酒比率显著降低(P0.05)。(6)高血压病程≥10年、血脂异常可独立预测中青年缺血性卒中脑血管狭窄的发生。结论:中青年缺血性卒中脑血管狭窄分布及危险因素有民族差异性。长期高血压、血脂异常仍是中青年缺血性卒中血管狭窄的主要因素。
[Abstract]:Objective: To explore the related factors of cerebral vascular stenosis in young and middle-aged patients with ischemic stroke, and the correlation factors and distribution differences of cerebral vascular stenosis in young and ischemic stroke in Hanzhoung and youth. Methods: a retrospective collection of young patients with ischemic stroke in 520 cases, according to the DSA or CTA in the head and neck were divided into vascular stenosis group 256 cases (male 176 cases, female 80 cases) and non vascular stenosis group 264 cases (male 200 cases, female 64 cases), according to the national vascular stenosis group was divided into: Uygur group 72 cases (male 52 cases, female 20 cases), 184 cases in the Han group (male 124 cases, female 60 cases). The clinical data were collected and compared. Results: (1) compared with the Han group, the rate of vascular lesions in the Uygur group was significantly higher than that in the Uygur group, and the rate of the posterior circulation and the anterior and posterior circulation decreased significantly (P0.05). (2) two groups were more common with intracranial vascular disease. Compared with Han nationality, the rate of intracranial vascular stenosis or occlusion in Uygur group increased significantly, and the rate of extracranial artery stenosis or occlusion and intracranial external joint lesion were reduced (P0.05). (3) compared with the Han nationality, the rate of light and moderate stenosis of the extracranial vessels in the Uygur group was higher, and the severe stenosis and occlusion rate were lower (P0.05). (4) compared with the Han group, the rate of vascular lesions of IVA, MCA and PCA in Uygur group decreased, and the rate of ACA, BA and I-ICA increased (P0.05). (5) compared with the Han Uygur group, group HHcy) and BMI more than or equal to 25kg/m2, the incidence of hypertension increased (P0.05), smoking and drinking rates decreased significantly (P0.05). (6) more than 10 years, the course of hypertension and dyslipidemia can occur young ischemic stroke independent prediction of cerebral vascular stenosis. Conclusion: there are ethnic differences in the distribution and risk factors of cerebral vascular stenosis in young and middle-aged ischemic stroke. Long term hypertension and dyslipidemia are still the main factors of vascular stenosis in young and middle-aged ischemic stroke.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R743.3

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