老年2型糖尿病患者甲状腺结节的影响因素分析

发布时间：2018-01-02 04:05

本文关键词：老年2型糖尿病患者甲状腺结节的影响因素分析　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:老年2型糖尿病(年龄≥60岁)患者甲状腺结节的患病情况及其相关影响因素。方法:2型糖尿病患者202例,其中,甲状腺结节患者91例(甲状腺结节组),非甲状腺结节组111例(对照组),收集患者病史、体重指数(BMI)、空腹血糖(FBG)、餐后2小时血糖(2hPBG)、糖化血红蛋白(HbA1c)、甘油三酯(TG)、胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、甲状腺相关激素水平等资料进行统计学分析。结果:年龄、性别、BMI、TC、HbA1c、LDL-C在两组间比较,差异有统计学意义(P0.05);两组间甲状腺功能指标比较示血清TSH、TPOAb差异有统计学意义(P0.05);病程、脉压、收缩压、腹围、吸烟史、HDL、TG、FBG、2hPBG在甲状腺结节组与非甲状腺结节组之间比较,差异均无统计学意义(P0.05)。多因素Logistic回归进行分析显示:性别、年龄、TC、HbA1c、BMI是甲状腺结节发生的危险因素。结论:对老年女性、肥胖、胆固醇升高的糖尿病患者进行甲状腺结节相关影像学检查具有重要临床意义。
[Abstract]:Objective: elderly patients with type 2 diabetes (age 60 years) factors in patients with thyroid nodules and related effects. Methods: 2 patients with type 202 diabetes, among them, 91 cases of patients with thyroid nodules (thyroid nodule group), 111 cases of non thyroid nodule group (control group) were collected, the history, body mass index (BMI), fasting blood glucose (FBG), 2 hour postprandial blood glucose (2hPBG), glycosylated hemoglobin (HbA1c), triglyceride (TG), cholesterol (TC), high density lipoprotein (HDL-C), low density lipoprotein (LDL-C), thyroid hormone levels and related data were analyzed statistically. Results: age. Gender, BMI, TC, HbA1c, LDL-C in the two groups, there were statistically significant differences between the two groups (P0.05); thyroid function indexes in serum TSH, TPOAb difference was statistically significant (P0.05); the course of disease, pulse pressure, systolic blood pressure, abdominal circumference, smoking history, HDL, TG, FBG, 2hPBG the thyroid nodule group and non thyroid Comparison between the nodule group, there were no significant differences (P0.05). Logistic regression analysis showed that gender, age, TC, HbA1c, BMI are risk factors for thyroid nodules. Conclusion: for elderly women, obesity, has important clinical significance in diabetic patients with elevated cholesterol were associated with thyroid nodules imaging.

【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R587.1;R581

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