不同海拔藏、汉族OSAS患者冠状动脉病变及颈动脉病变的研究

发布时间：2018-01-02 07:26

本文关键词：不同海拔藏、汉族OSAS患者冠状动脉病变及颈动脉病变的研究　出处：《青海大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨在不同海拔环境下藏族、汉族阻塞性睡眠呼吸暂停综合征(OSAS)患者冠状动脉及颈动脉病变特点,初步明确不同的海拔环境是否对OSAS患者发生心脑血管疾病的风险存在影响,了解藏、汉族OSAS患者之间是否存在民族差别,以引起更多人对OSAS的重视,从而减少心脑血管疾病的发生。方法:对研究对象采用多导睡眠监测仪进行睡眠监测,同期完成血脂、24h动态血压、冠状动脉CT、颈动脉彩超等项目检查,设OSAS伴高血压组为试验组(OSAS组),高血压组为对照组(高血压组);结果:1.西宁地区藏、汉族OSAS患者冠状动脉及颈动脉病变程度较同海拔、同民族对照组严重,差异有统计学意义(P0.05);2.玉树地区藏、汉族OSAS患者冠状动脉及颈动脉病变程度与同海拔、同民族对照组相比,组间无差异(P0.05);3.西宁地区藏、汉族OSAS患者冠状动脉及颈动脉病变程度较玉树地区藏、汉族OSAS患者严重,差异有统计学意义(P0.05);4.同一海拔下,藏族OSAS患者与汉族OSAS患者相比,冠状动脉及颈动脉病变程度无差异(P0.05);结论:1.西宁地区OSAS患者冠状动脉及颈动脉粥样硬化程度可能高于玉树地区,其发生心脑血管疾患的风险也增高。2.在同海拔环境下生活的藏、汉族OSAS患者发生心脑血管疾患的风险可能无差别。
[Abstract]:Objective: To explore the Tibetan in different altitude, the Han nationality of obstructive sleep apnea syndrome (OSAS) patients with carotid and coronary artery lesion characteristics, preliminary define different altitude environment affect the risk of cardiovascular disease in patients with OSAS to understand whether there is difference between ethnic Tibetan, Han OSAS patients, in order to attract more people pay more attention to the OSAS, thereby reducing the incidence of cardiovascular and cerebrovascular diseases. Methods: the study object of the sleep monitoring polysomnography performed at the same time, blood lipids, 24h ambulatory blood pressure, coronary artery CT and carotid artery color Doppler ultrasound examination project, a OSAS with hypertension group as experimental group (OSAS group), hypertension group group (hypertension group); results: 1. reservoirs in Xining region, OSAS in patients with coronary artery and carotid artery lesions compared with altitude, with the national control group, the difference was statistically significant (P0.05); 2. jade The tree in Tibetan and Han OSAS patients, carotid and coronary artery lesions with the same altitude, compared with the national control group, no significant difference between groups (P0.05); 3. in Xining Tibetan, Han OSAS patients with coronary artery and carotid artery lesions was more serious in Yushu area Tibetan, Han OSAS patients, the difference was statistically significant (P0.05) 4.; the same altitude, compared to Tibetan OSAS patients and Han OSAS patients, no difference between carotid and coronary artery lesions (P0.05); conclusion: 1. OSAS patients in the Xining area of coronary artery and carotid atherosclerosis may be higher than the Yushu region, the occurrence of cardiovascular disease risk also increased.2. at the same altitude of life Tibet, the risk of cardiovascular and cerebrovascular diseases in Han OSAS patients may have no difference.

【学位授予单位】：青海大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R766

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