新疆地区巴雷特食管病理分型分析

发布时间：2018-01-19 21:17

本文关键词： 新疆地区巴雷食管病理分型分析　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:研究新疆地区人群中巴雷特食管(Barrett's esophagus BE)的病理类型、内镜分型、临床症状的关系,及维汉两族人群是否存在差异。方法:对604例行电子内镜检查并行活组织检查确诊为BE的维汉患者进行病理类型、内镜分型、临床症状之间的关系进行相关分析,并对维吾尔族及汉族人群中BE进行比较。结果:(1)BE总检出率为1.29%,男:女为1.21:1,平均发病年龄为(50.84±10.89)岁。(2)BE病理分型中以贲门型(44%)、胃底型(48%)多见,三种病理类型的平均发病年龄(P0.05)、平均BMI值(P0.05)比较差异有统计学意义。BE内镜分型中以短节段巴雷特食管(Short segmental Barrett's esophagus SSBE)为主占78.64%,岛型多见占73.04%。BE患者中有症状者占66.06%,常见的临床症状为反酸、烧心、上腹不适、胸骨后不适等。幽门螺杆菌(Helicobacter pylori Hp)阳性率为29.80%。(3)维吾尔族BE检出率1.04%,汉族BE检出率1.46%。病理类型:维汉两族均以贲门型、胃底型多见,肠型少见,但维汉两族人群的贲门型、肠化型分布的构成比较差异有统计学意义。两族中内镜下均以SSBE为主,岛型多见。维汉两族在年龄、BMI值、食管炎等比较差异具有统计学意义(P0.05)。结论:新疆地区BE总的检出率及各自的检出率与国内各地区BE检出率相接近,BE三种病理类型中以贲门型及胃底型为主,其平均发病年龄明显提前,且贲门型BMI值偏大。维吾尔族的发病年龄较汉族提前,BMI及食管炎的发生率较汉族大,维汉两族人群贲门型及肠化型BE分布的构成不同。因此新疆地区中年、BMI值偏大的人群应定期行内镜下监测,尤其是维吾尔族人群。
[Abstract]:Objective: to study the pathological types, endoscopic classification and clinical symptoms of Barrett's esophagus in Barrett's esophagus in Xinjiang. Methods: 604 Uygur Han patients who were diagnosed as be by electronic endoscopy and biopsy were divided into pathological type and endoscope type. The relationship between clinical symptoms was analyzed and be in Uygur and Han population was compared. Results the total detection rate of be was 1.29% for male: female 1.21: 1. The average age of onset was 50.84 卤10.89 years old. In the pathological classification of cardia type, cardia type and stomach fundus type were more common. The mean age of onset of the three pathological types was P 0.05). The difference of mean BMI value (P 0.05) was statistically significant. In the endoscopic typing of be, the short segment of Barrett's esophagus (. Short segmental Barrett's esophagus SSBE accounted for 78.64%. Island type accounted for 73.04.be patients with symptoms accounted for 66.06, common clinical symptoms for acid reflux, heartburn, upper abdomen discomfort. Helicobacter pylori pylori positive rate of Helicobacter pylori was 29.80%. The detection rate of be in Uygur nationality was 1.04%. The detection rate of be in Han nationality was 1.46. Pathological type: both Uygur and Han nationalities had cardia type, gastric fundus type was more common, intestinal type was rare, but Uygur and Han nationality population had cardia type. The distribution of intestinal metaplasia was significantly different between the two groups under endoscopy, and the island type was more common. Uygur and Han nationality in age and SSBE value. The difference of esophagitis was statistically significant (P 0.05). Conclusion: the total detection rate of be and its detection rate in Xinjiang are close to those in China. Among the three types of be, cardia type and gastric fundus type were the main pathological types. The average onset age of be was significantly earlier than that of the Han nationality, and the BMI value of the gastric cardia type was higher. The onset age of Uygur nationality was earlier than that of Han nationality. The incidence of BMI and esophagitis was higher than that of Han nationality. The distribution of be of cardia type and intestinal type was different between Uygur and Han ethnic groups. Especially the Uygur people.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R571

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