基于数据挖掘技术研究王旭教授治疗糖尿病的经验及复法组方结构

发布时间：2018-01-24 14:44

本文关键词： 糖尿病数据挖掘复法王旭经验总结　出处：《南京中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:以收集的导师门诊治疗糖尿病的医案为基础,采用数据挖掘技术对导师临证病案进行分析,结合导师临证典型医案方剂解构,总结导师临床辨治糖尿病的经验及复法组方结构,使其源于临床,高于临床,以冀回归指导临床。方法:本次研究主要分为两大部分。第一部分通过跟随导师门诊学习,对导师治疗糖尿病的医案进行全面收集、整理,严格按照纳入标准、排除标准筛选数据,将符合条件的193例病例共计340诊次的临床资料利用Medcase V3.2数据记录挖掘系统建立病案采集、存贮数据库,运用频数分布、关联规则分析等方法挖掘分析其临床表现、舌苔、脉象、处方用药的特点和各自之间的联系,并对挖掘结果进行分析、归纳、总结。第二部分通过筛选导师临床诊治糖尿病及其并发症的典型医案,对其进行方剂解构分析,总结导师复法治疗糖尿病的组方结构。结果:通过数据挖掘研究得出:193例患者中男性86例,女性107例,年龄最大91岁,最小21岁。临床症状频次超过60次的有:口干、视物模糊、尿沫、寐差、乏力、神疲、肢麻,分别占 34.71%、32.94%、29.71%、29.41%、27.35%、22.35%、20.29%。舌质主要为质红65.88%、质淡红23.53%,舌苔频次大于80次的有苔薄白、苔薄,频率分别为27.94%、25.88%。脉象频次大于100次的有细脉、滑脉、弦脉,频率分别为51.18%、38.82%、30.88%。本次研究共涉及中药251味,累计用药频次5328次,诊次频率大于50%的高频药物有地骨皮、枸杞子、葛根、山药四味。共涉及药物种类14种,主要为清热药、补气药、活血化瘀药、补阴药、补血药、补阳药,其中清热药占首重。通过典型医案解构分析,总结导师的组方特点有阴阳双补、气血互调、多脏兼顾、清滋并用等。结论:通过研究发现,糖尿病发病人群多为中、老年人群,在青年人群中的发病率亦较高。王旭教授辨治糖尿病多从虚损、热郁、瘀阻立论,基本治法为清热活血,养阴益气。复法组方特点有阴阳双补、气血互调、多脏兼顾、清滋并用等。
[Abstract]:Objective: based on the medical records of tutor outpatient treatment of diabetes mellitus, data mining technology was used to analyze the clinical medical records of mentors, and to deconstruct the typical prescriptions of mentors' clinical cases. Summing up the experience of clinical differentiation and treatment of diabetes mellitus and the compound prescription structure, so that it originated from the clinical, higher than the clinical. Methods: this study is divided into two parts. The first part is to collect and organize the medical records of diabetes treated by mentors through out-patient study with mentors, and strictly follow the inclusion criteria. Excluding the standard screening data, the clinical data of 193 cases were collected and stored by Medcase V3.2 data mining system. Using frequency distribution, association rules analysis and other methods mining analysis of its clinical manifestations, tongue coating, pulse, prescription drug use characteristics and the relationship between each other, and mining results are analyzed and summarized. Summary. The second part through screening mentors clinical diagnosis and treatment of diabetes and its complications of typical medical records, the prescription deconstruction analysis. Results: according to data mining, 86 cases of male and 107 cases of female were found to be male, 107 cases were female, the oldest age was 91 years old. The youngest 21 years, the frequency of clinical symptoms more than 60 times: dry mouth, blurred vision, urine foam, insomnia, fatigue, fatigue, limb anaesthesia, 34.71%, 32.94%. 29.41: 27.35B 22.35B 20.29.The tongue quality is mainly qualitative red 65.88, light red 23.53, tongue coating frequency more than 80 times with thin white fur and thin fur. The frequencies of pulse frequency were 27.94 and 25.88.The frequency of pulse frequency more than 100 times was 51.1838.82%, and the frequency of smooth vein and chord vein were 51.18% and 38.82%, respectively. 30.88. this study involved 251kinds of traditional Chinese medicine, the cumulative frequency of drug use 5328 times, the frequency of diagnosis more than 50% times of high-frequency drugs have the bone skin, wolfberry, Pueraria root. There are 14 kinds of drugs involved in yam. They are mainly heat-clearing medicine, tonifying qi medicine, activating blood circulation medicine, tonifying yin medicine, blood tonifying medicine, reinforcing yang medicine, among which heat-clearing medicine is the most important one, which is analyzed by deconstruction of typical medical records. Summing up the teacher's prescription characteristics are Yin and Yang double tonifying, qi and blood mutual regulation, both dirty and clean, and so on. Conclusion: through the study, the diabetes incidence population is mostly middle, elderly people. The incidence of diabetes in young people is also high. Professor Wang Xu differentiation and treatment of diabetes from deficiency, heat depression, stasis theory, the basic treatment method for clearing heat and activating blood, nourishing Yin and Qi. The compound method has the characteristics of Yin and Yang, Qi-blood intermodulation. How dirty, how dirty, and so on.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R249;R259

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