甲状腺良性结节微波消融和手术切除临床疗效和安全性对比分析

发布时间：2018-02-02 02:17

本文关键词： 甲状腺结节良性微波消融并发症　出处：《中国介入影像与治疗学》2017年08期 　论文类型：期刊论文

【摘要】：目的对比分析甲状腺良性结节患者微波消融和手术切除的临床效果和安全性。方法收集100例甲状腺良性结节患者影像和临床资料,其中微波消融术治疗44例53个结节(消融组),外科手术治疗56例60个结节(手术组)。比较2组患者治疗后1、3、6、12个月结节消退率,观察结节体积随时间变化趋势,并比较2组术后不良反应、住院时间等情况。结果消融组治疗后1、3、6、12个月结节消退率分别为54.55%、72.73%、95.45%、95.45%,手术组均为100%,治疗后1、3个月结节消退率消融组低于手术组(P均0.001),治疗后6、12个月结节消退率2组间差异无统计学意义(P均=0.245)。消融组术后结节体积随时间呈下降趋势,6个月前结节体积缩小幅度较大,6个月后结节体积缩小幅度降低。消融组术后甲状腺功能低下发生率低于手术组(P=0.019),血肿、感染、声音嘶哑、甲状旁腺损伤发生率2组间差异无统计学意义(P均0.05)。消融组平均住院时间短于手术组(t=-8.499,P=0.001)。结论微波消融技术治疗甲状腺良性结节能保证疗效,且并发症少、创伤小、住院时间短,其临床应用前景广阔。
[Abstract]:Objective to compare the clinical efficacy and safety of microwave ablation and surgical resection in patients with benign thyroid nodules. Microwave ablation was performed in 44 patients with 53 nodules (ablation group) and surgical treatment in 56 patients (60 nodules). The changes of nodule volume with time were observed, and the adverse reactions and hospital stay were compared between the two groups. Results the regression rates of nodules in the ablation group were 54.55% at 1: 3 and 12 months, respectively. 72.73 and 95.455 and 95.45%, 100 in the operation group. The regression rate of nodule in the ablation group was lower than that in the operation group at 1 and 3 months after treatment (P = 0.001), and 6 months after treatment. There was no significant difference in the regression rate of nodules between the two groups at 12 months. The nodule volume in the ablation group decreased with time, and the nodule volume decreased significantly before 6 months. The incidence of hypothyroidism in the ablation group was lower than that in the operation group (P < 0.019), hematoma, infection and hoarseness. There was no significant difference in the incidence of parathyroid injury between the two groups (P < 0.05). The average hospital stay in the ablation group was shorter than that in the operation group (P < 0.05). Conclusion Microwave ablation technique for benign thyroid nodules can ensure curative effect, with fewer complications, less trauma and shorter hospital stay. It has a broad clinical application prospect.
【作者单位】：广西医科大学附属肿瘤医院介入科;
【分类号】：R653
【正文快照】： 无统计学意义(P均0.05)。消融组平均住院时间短于手术组(t=-8.499,P=0.001)。结论微波消融技术治疗甲状腺良性结节能保证疗效,且并发症少、创伤小、住院时间短,其临床应用前景广阔。甲状腺结节是来源于甲状腺组织、位于甲状腺实质内或突出甲状腺外、具有占位性效应的一系列疾

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