胆汁反流性胃炎的证素分布特点及相关因素研究

发布时间：2018-05-10 06:53

  本文选题：胆汁反流性胃炎 + 证素　； 参考：《南京中医药大学》2017年硕士论文

【摘要】：目的:参考证素辨证体系,通过对胆汁反流性胃炎患者临床资料分析,初步探究其证素分布规律及相关因素,完善本病中医辨证体系,指导临床干预及治疗。方法:收集191例胆汁反流性胃炎患者的病例资料,根据问卷调查表搜集的相关信息,参考朱文锋教授编写的《证素辨证学》中"症候辨证量表"提取相关证素,建立数据库,运用统计学方法,总结胆汁反流性胃炎的证素分布特点并分析其与多种因素的相关性。结果:本次研究人群发病年龄以51-70岁最多,女性患者多于男性患者,以职员和工人较多。饮酒和辛辣饮食为可能的危险因素。胆汁反流性胃炎的镜下反流程度以Ⅰ级为主。Hp感染率在本病中占14.14%。人群的病理组织学检查可见较高程度腺体萎缩及肠化,检出阳性率为25.13%和21.99%;患者主要的病位证素有胃、肝、脾、胆、大肠,其中胃所占比例最高为76.71%;肝次之,为56.85%;脾、胆及大肠所占比例依次为25.34%、10.96%、6.16%。病位证素组合以双病位最多(59.59%),其次是单病位(33.56%),其他病位组合少见(6.85%)。病位证素组合以肝胃最多,胃及脾胃次之。主要的病性证素有气滞(36.99%)、热(28.77%)、气虚(26.03%)、血瘀(21.92%)、阴虚(19.86%)、食积(13.70%)、湿(8.22%)、阳虚(4.79%)、寒(3.42%)。双病性组合较多,单病性次之。实证为93例(63.70%),虚证22例(15.07%),虚实夹杂证31例(21.23%)。不同性别的胆汁反流性胃炎患者病位证素分布有差异性。本病的病性证素分布与病理相关。其证素分布与年龄、Hp感染、镜下反流程度无相关性。结论:本次研究中胆汁反流性胃炎患者女性多于男性,以51-70岁为高发年龄段。Hp阳性率为14.14%。镜下反流程度以Ⅰ级为主。病位证素主要有胃、肝、脾、胆、大肠,病位组合以肝胃为主。其病性证素有气滞、热、气虚、血瘀、阴虚、食积、湿、阳虚、寒;实证以气滞和热最多,虚症以气虚、阴虚为主。病性组合以双病性最多。实证较虚症和虚实夹杂证最多。不同性别的胆汁反流性胃炎患者病位证素分布有差异性。本病的病性证素分布与病理相关。胆汁反流性胃炎的证素分布与年龄、Hp感染、镜下反流程度无相关性。
[Abstract]:Objective: to analyze the clinical data of patients with bile reflux gastritis with reference to syndrome differentiation system, and to explore the distribution of syndromes and related factors, improve the syndrome differentiation system of TCM, and guide clinical intervention and treatment. Methods: the data of 191 patients with bile reflux gastritis were collected. According to the relevant information collected from the questionnaire, the syndrome differentiation scale compiled by Professor Zhu Wenfeng was used to extract the relevant syndromes and to establish a database. The distribution of syndromes in bile reflux gastritis was summarized by statistical method and its correlation with many factors was analyzed. Results: the age of onset in this study was 51-70 years old, female patients were more than male patients, staff and workers were more. Alcohol consumption and spicy diet are possible risk factors. The degree of reflux in bile reflux gastritis was mainly grade 鈪，

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